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Pharmacology Research Articles

Synergistic effect of silymarin and standardized extract of Phyllanthus amarus against CCl4-induced hepatotoxicity in Rattus norvegicus
Fulltext Access 9 Pages 2008
Changes in antioxidant defense status in hypercholesterolemic rats treated with Ajuga iva
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Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled study
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Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented malignant melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis
Fulltext Access 9 Pages 2008
Comparative in vitro study on the anti-herpetic effect of phytochemically characterized aqueous and ethanolic extracts of Salvia officinalis grown at two different locations
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Chemoprofile and bioactivities of Taverniera cuneifolia (Roth) Arn.: A wild relative and possible substitute of Glycyrrhiza glabra L.
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Differential protein expression in mouse splenic mononuclear cells treated with polysaccharides from spores of Ganoderma lucidum
Fulltext Access 9 Pages 2008
A comparable, chemical and pharmacological analysis of the traditional Chinese medicinal herbs Oldenlandia diffusa and O. corymbosa and a new valuation of their biological potential
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Pharmacokinetic studies of a Chinese triple herbal drug formula
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Protective effect of a standardized Ginkgo extract (ginaton) on renal ischemia/reperfusion injury via suppressing the activation of JNK signal pathway
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The effect of Camphor–Crataegus berry extract combination on blood pressure and mental functions in chronic hypotension – A randomized placebo controlled double blind design
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Efficacy of an aqueous Pelargonium sidoides extract against herpesvirus
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Suppressive effects of bee venom on the immune responses in collagen-induced arthritis in rats
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Effects of aqueous hop (Humulus Lupulus L.) extract on vascular reactivity in rats: Mechanisms and influence of gender and hormonal status
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Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents
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Panaxydol and panaxynol protect cultured cortical neurons against Aβ25–35-induced toxicity
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Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis
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Predictive validity of animal pain models? A comparison of the pharmacokinetic–pharmacodynamic relationship for pain drugs in rats and humans
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Supersensitivity to μ-opioid receptor-mediated inhibition of the adenylyl cyclase pathway involves pertussis toxin-resistant Gα protein subunits
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Inhibition of NMDA-gated ion channels by bis(7)-tacrine: Whole-cell and single-channel studies
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Stargazin modulates AMPA receptor antagonism
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Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain
Fulltext Access 9 Pages 2008
Proteasomal degradation of IRS-2, but not IRS-1 by calcineurin inhibition: Attenuation of insulin-like growth factor-I-induced GSK-3β and ERK pathways in adrenal chromaffin cells
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A role for nuclear β-catenin in SNRI antidepressant-induced hippocampal cell proliferation
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The selective 5-HT6 receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats
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NIAID resources for developing new therapies for severe viral infections
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Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity?
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The cannabinoid CB1 receptor antagonist SR141716A (Rimonabant) enhances the metabolic benefits of long-term treatment with oleoylethanolamide in Zucker rats
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Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro
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Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice
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Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling
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The CYP2B2 5′ flank contains a complex glucocorticoid response unit
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Neuronal nicotinic acetylcholine receptors: From the genetic analysis to neurological diseases
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The role of helioxanthin in inhibiting human hepatitis B viral replication and gene expression by interfering with the host transcriptional machinery of viral promoters
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Adenovirus-mediated shRNA interference against porcine circovirus type 2 replication both in vitro and in vivo
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Characterization of resistance mutations against HCV ketoamide protease inhibitors
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Potential of antiviral therapy and prophylaxis for controlling RNA viral infections of livestock
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Treatment of yellow fever
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Mechanisms of ischemic brain damage
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Applications of bioluminescence imaging to antiviral research and therapy: Multiple luciferase enzymes and quantitation
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Efficacy of cationic lipid–DNA complexes (CLDC) on hepatitis B virus in transgenic mice
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Anti-HSV activity of digitoxin and its possible mechanisms
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Genotypic detection of acyclovir-resistant HSV-1: Characterization of 67 ACV-sensitive and 14 ACV-resistant viruses
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Association between diabetes patients' knowledge about medications and their blood glucose control
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Content analysis methods for conducting research in social and administrative pharmacy
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A descriptive study of self-medication practices among Palestinian medical and nonmedical university students
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Utilization of a community pharmacy-operated national drug information call center in Finland
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Self-efficacy in counseling in Norwegian chain pharmacies: A cross-sectional study
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Effect of Ninjin-yoei-to (Rensheng-Yangrong-Tang) on olfactory behavior after olfactory nerve transection
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A mannose-binding lectin from Sophora flavescens induces apoptosis in HeLa cells
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Effects of acute oral Δ9-tetrahydrocannabinol and standardized cannabis extract on the auditory P300 event-related potential in healthy volunteers
Fulltext Access 9 Pages 2008
Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
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The BTB/kelch protein, KRIP6, modulates the interaction of PICK1 with GluR6 kainate receptors
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The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats
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Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression
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Lipid rafts, cholesterol, and the brain
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Evaluation of the enantioselective antiallodynic and pharmacokinetic profile of propylisopropylacetamide, a chiral isomer of valproic acid amide
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Habituation and sensitization to heat and cold pain in women with fibromyalgia and healthy controls
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Communications orales - Ateliers thématiques spécifiques
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Communications orales - cours supérieurs
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Comment un réseau douleur régional peut-il améliorer la prise en charge des patients atteints de douleur chronique ? Discussion à partir des résultats d'une étude réalisée chez 166 patients pris en charge dans les structures douleur de Franche-Comté
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IONSYS™ versus morphine PCA: Analysis of the current literature using a Bayesian approach
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Documentation of postoperative pain by nurses in surgical wards
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An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown
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α1-Noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access
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5-HT1A receptors in the dorsal hippocampus mediate the anxiogenic effect induced by the stimulation of 5-HT neurons in the median raphe nucleus
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Striatal dopamine D2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males
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Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: A double-blind placebo-controlled trial
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Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects
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Antagonism of glutamatergic NMDA and mGluR5 receptors decreases consumption of food in baboon model of binge-eating disorder
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The role of dopamine in alcohol self-administration in humans: Individual differences
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Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies
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The triple monoaminergic reuptake inhibitor DOV 216,303 has antidepressant effects in the rat olfactory bulbectomy model and lacks sexual side effects
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Distinct contributions of dopamine receptors in the nucleus accumbens core or shell to established cocaine reinforcement under a second-order schedule
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8-week, single-blind, randomized trial comparing risperidone versus olanzapine augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive–compulsive disorder
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Desipramine potentiation of the acute depressant effects of ethanol: Modulation by α2-adrenoreceptors and stress
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Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory
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Partial neuroprotection with low-dose infusion of the α2-adrenergic receptor agonist clonidine after severe hypoxia in preterm fetal sheep
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Carbenoxolone impairs LTP and blocks NMDA receptors in murine hippocampus
Fulltext Access 9 Pages 2008
The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism
Fulltext Access 9 Pages 2008
AM404, an anandamide transport inhibitor, reduces plasma extravasation in a model of neuropathic pain in rat: Role for cannabinoid receptors
Fulltext Access 9 Pages 2008
Serotonin and GI clinical disorders
Fulltext Access 9 Pages 2008
Assessing human 5-HT function in vivo with pharmacoMRI
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Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice
Fulltext Access 9 Pages 2008
Transcriptional regulation at a HTR1A polymorphism associated with mental illness
Fulltext Access 9 Pages 2008
3,4-Methylenedioxy-N-methamphetamine (ecstasy) promotes the survival of fetal dopamine neurons in culture
Fulltext Access 9 Pages 2008
Roles of ectodomain and transmembrane regions in ethanol and agonist action in purinergic P2X2 and P2X3 receptors
Fulltext Access 9 Pages 2008
Inhibition of glial inflammatory activation and neurotoxicity by tricyclic antidepressants
Fulltext Access 9 Pages 2008
Cannabinoid receptor 1 (CNR1) gene: Impact on antidepressant treatment response and emotion processing in Major Depression
Fulltext Access 9 Pages 2008
Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration
Fulltext Access 9 Pages 2008
The effects of acute and repeated oroxylin A treatments on Aβ25–35-induced memory impairment in mice
Fulltext Access 9 Pages 2008
Type-3 metabotropic glutamate receptors negatively modulate bone morphogenetic protein receptor signaling and support the tumourigenic potential of glioma-initiating cells
Fulltext Access 9 Pages 2008
Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: Blockade by the mGluR5 antagonist MPEP
Fulltext Access 9 Pages 2008
Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors
Fulltext Access 9 Pages 2008
Dual neurotoxic and neuroprotective role of metabotropic glutamate receptor 1 in conditions of trophic deprivation – Possible role as a dependence receptor
Fulltext Access 9 Pages 2008
Switch in the expression of mGlu1 and mGlu5 metabotropic glutamate receptors in the cerebellum of mice developing experimental autoimmune encephalomyelitis and in autoptic cerebellar samples from patients with multiple sclerosis
Fulltext Access 9 Pages 2008
Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from mouse cortical nerve endings
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Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells
Fulltext Access 9 Pages 2008
Heterogeneity of nicotinic acetylcholine receptor expression in the caudal nucleus of the solitary tract
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Neuroendocrine, behavioral and macrophage activity changes induced by picrotoxin effects in mice
Fulltext Access 9 Pages 2008
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