Disulfiram promotes the conversion of carcinogenic cadmium to a proteasome inhibitor with pro-apoptotic activity in human cancer cells Fulltext Access 9 Pages 2008
Sprague-Dawley rats display metabolism-mediated sex differences in the acute toxicity of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) Fulltext Access 9 Pages 2008
An underlying role for hepatobiliary dysfunction in cyclosporine A nephrotoxicity Fulltext Access 9 Pages 2008
PPARα regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes Fulltext Access 9 Pages 2008
Mitochondria as an important target in heavy metal toxicity in rat hepatoma AS-30D cells Fulltext Access 9 Pages 2008
Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2+/− mice: Two-stage oxidative injury Fulltext Access 9 Pages 2008
Delphinidin inhibits cell proliferation and invasion via modulation of Met receptor phosphorylation Fulltext Access 9 Pages 2008
Cytogenetic status and oxidative DNA-damage induced by atorvastatin in human peripheral blood lymphocytes: Standard and Fpg-modified comet assay Fulltext Access 9 Pages 2008
Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-κB pathway: New lessons from endotoxin and ribotoxic deoxynivalenol Fulltext Access 9 Pages 2008
A cell-based in vitro alternative to identify skin sensitizers by gene expression Fulltext Access 9 Pages 2008
Teratogen-induced distortions in the classical NF-κB activation pathway: Correlation with the ability of embryos to survive teratogenic stress Fulltext Access 9 Pages 2008
Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat Fulltext Access 9 Pages 2008
Involvement of SREBPs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced disruption of lipid metabolism in male guinea pig Fulltext Access 9 Pages 2008
From topical antidote against skin irritants to a novel counter-irritating and anti-inflammatory peptide Fulltext Access 9 Pages 2008
Delta-9-tetrahydrocannabinol accumulation, metabolism and cell-type-specific adverse effects in aggregating brain cell cultures Fulltext Access 9 Pages 2008
Cytotoxic, genotoxic and cell-cycle disruptive effects of thio-dimethylarsinate in cultured human cells and the role of glutathione Fulltext Access 9 Pages 2008
Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: Stimulation of interleukin-8 secretion, potentiation of interleukin-1β effect and increase in the transepithelial Fulltext Access 9 Pages 2008
Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation Fulltext Access 9 Pages 2008
Molecular mechanism of reduction in pregnenolone synthesis by cigarette smoke Fulltext Access 9 Pages 2008
Copper accumulation and lipid oxidation precede inflammation and myelin lesions in N,N-diethyldithiocarbamate peripheral myelinopathy Fulltext Access 9 Pages 2008
Inhibition of c-Jun N-terminal kinase sensitizes tumor cells to flavonoid-induced apoptosis through down-regulation of JunD Fulltext Access 9 Pages 2008
An inventory of the ethnoveterinary practices for reproductive disorders in cattle and buffaloes, Sargodha district of Pakistan Fulltext Access 10 Pages 2008
Characterization of early events involved in human dendritic cell maturation induced by sensitizers: Cross talk between MAPK signalling pathways Fulltext Access 10 Pages 2008
Temporal effect of Guanxin No. 2 on cardiac function, blood viscosity and angiogenesis in rats after long-term occlusion of the left anterior descending coronary artery Fulltext Access 10 Pages 2008
Naturally-occurring estradiol-17β-fatty acid esters, but not estradiol-17β, preferentially induce mammary tumorigenesis in female rats: Implications for an important role in human breast cancer Fulltext Access 10 Pages 2008
Modulation of pulmonary inflammatory responses and antimicrobial defenses in mice exposed to diesel exhaust Fulltext Access 10 Pages 2008
Microarray analysis in rat liver slices correctly predicts in vivo hepatotoxicity Fulltext Access 10 Pages 2008
Gene expression profiling in rat liver treated with compounds inducing phospholipidosis Fulltext Access 10 Pages 2008
Gut modulatory, blood pressure lowering, diuretic and sedative activities of cardamom Fulltext Access 10 Pages 2008
Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest Fulltext Access 10 Pages 2008
Dangnyohwan improves glucose utilization and reduces insulin resistance by increasing the adipocyte-specific GLUT4 expression in Otsuka Long-Evans Tokushima Fatty rats Fulltext Access 10 Pages 2008
The Medication Assessment Program: Comprehensive medication assessments for persons taking multiple medications for chronic diseases Fulltext Access 10 Pages 2008
Ethnobotanical study of medicinal plants used by Hakka in Guangdong, China Fulltext Access 10 Pages 2008
Effects of Cordyceps sinensis, Cordyceps militaris and their isolated compounds on ion transport in Calu-3 human airway epithelial cells Fulltext Access 10 Pages 2008
A comparative study on medicinal plants used in Akha's traditional medicine in China and Thailand, cultural coherence or ecological divergence? Fulltext Access 10 Pages 2008
Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor Fulltext Access 10 Pages 2008
Proposal open for discussion: defining agreed diagnostic procedures in experimental diabetes research Fulltext Access 10 Pages 2008
Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk Fulltext Access 10 Pages 2008
Toxicological relationships between proteins obtained from protein target predictions of large toxicity databases Fulltext Access 10 Pages 2008
Pyrrolidine dithiocarbamate-zinc(II) and -copper(II) complexes induce apoptosis in tumor cells by inhibiting the proteasomal activity Fulltext Access 10 Pages 2008
Endothelial glutathione-S-transferase A4-4 protects against oxidative stress and modulates iNOS expression through NF-κB translocation Fulltext Access 10 Pages 2008
Pharmacist-provided medication therapy management (part 1): Provider perspectives in 2007 Fulltext Access 10 Pages 2008
Orai1–STIM1 formed store-operated Ca2+ channels (SOCs) as the molecular components needed for Pb2+ entry in living cells Fulltext Access 10 Pages 2008
Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-α following ozone inhalation Fulltext Access 10 Pages 2008
Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells Fulltext Access 10 Pages 2008
Effect of ergot alkaloids associated with fescue toxicosis on hepatic cytochrome P450 and antioxidant proteins Fulltext Access 10 Pages 2008
PharmacistCARE: Description of a pharmacist care service and lessons learned along the way Fulltext Access 10 Pages 2008
Impact of pharmacist interventions on seeking of medical care by migraineurs Fulltext Access 10 Pages 2008
Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver Fulltext Access 10 Pages 2008
Role of vitamin C transporters and biliverdin reductase in the dual pro-oxidant and anti-oxidant effect of biliary compounds on the placental-fetal unit in cholestasis during pregnancy Fulltext Access 10 Pages 2008
Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line Fulltext Access 10 Pages 2008
Tissue dosimetry, metabolism and excretion of pentavalent and trivalent dimethylated arsenic in mice after oral administration Fulltext Access 10 Pages 2008
Lipid homeostasis and oxidative stress in the liver of male rats exposed to perfluorododecanoic acid Fulltext Access 10 Pages 2008
Perceptions of Medicare Part D enrollees about pharmacists and their role as providers of medication therapy management Fulltext Access 10 Pages 2008
Collaborations to facilitate success of community pharmacy practice-based research networks Fulltext Access 10 Pages 2008
The Medication Assessment Program: Comprehensive medication assessments for persons taking multiple medications for chronic diseases Fulltext Access 10 Pages 2008
Phototoxicity and cytotoxicity of fullerol in human lens epithelial cells Fulltext Access 10 Pages 2008
Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase Fulltext Access 10 Pages 2008
o,p′-DDT induces cyclooxygenase-2 gene expression in murine macrophages: Role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways Fulltext Access 10 Pages 2008
How can biologically-based modeling of arsenic kinetics and dynamics inform the risk assessment process? - A workshop review Fulltext Access 10 Pages 2008
Role of rat sodium/phosphate cotransporters in the cell membrane transport of arsenate Fulltext Access 10 Pages 2008
Novel function of glutathione transferase in rat liver mitochondrial membrane: Role for cytochrome c release from mitochondria Fulltext Access 10 Pages 2008
Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity Fulltext Access 10 Pages 2008
Chemical mixtures: Evaluation of risk for child-specific exposures in a multi-stressor environment Fulltext Access 10 Pages 2008
Intervention of d-glucose ameliorates the toxicity of streptozotocin in accessory sex organs of rat Fulltext Access 10 Pages 2008
Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2 Fulltext Access 10 Pages 2008
The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion Fulltext Access 10 Pages 2008
Reciprocal regulation of extracellular signal regulated kinase 1/2 and mitogen activated protein kinase phosphatase-3 Fulltext Access 10 Pages 2008
Matrix metalloproteinase-2 and -9 are induced differently by metal nanoparticles in human monocytes: The role of oxidative stress and protein tyrosine kinase activation Fulltext Access 10 Pages 2008
Chlordecone, a mixed pregnane X receptor (PXR) and estrogen receptor alpha (ERα) agonist, alters cholesterol homeostasis and lipoprotein metabolism in C57BL/6 mice Fulltext Access 10 Pages 2008
Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury Fulltext Access 10 Pages 2008
Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein Fulltext Access 10 Pages 2008
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse Fulltext Access 10 Pages 2008
Modulation of DNA polymerase beta-dependent base excision repair in cultured human cells after low dose exposure to arsenite Fulltext Access 10 Pages 2008
Single whole-body exposure to sarin vapor in rats: Long-term neuronal and behavioral deficits Fulltext Access 10 Pages 2008
High fat diet-fed obese rats are highly sensitive to doxorubicin-induced cardiotoxicity Fulltext Access 10 Pages 2008
Particles from wood smoke and traffic induce differential pro-inflammatory response patterns in co-cultures Fulltext Access 10 Pages 2008
Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: A rapid invivo screening method for nanotoxicity Fulltext Access 10 Pages 2008
Opposing roles for caspase and calpain death proteases in l-glutamate-induced oxidative neurotoxicity Fulltext Access 10 Pages 2008
Fluorescence in situ hybridization techniques (FISH) to detect changes in CYP19a gene expression of Japanese medaka (Oryzias latipes) Fulltext Access 10 Pages 2008
Lactational exposure to hexavalent chromium delays puberty by impairing ovarian development, steroidogenesis and pituitary hormone synthesis in developing Wistar rats Fulltext Access 10 Pages 2008
Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity Fulltext Access 10 Pages 2008
Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK Fulltext Access 10 Pages 2008
Mechanism of erythrocyte death in human population exposed to arsenic through drinking water Fulltext Access 10 Pages 2008
Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS Fulltext Access 10 Pages 2008
Comparative genomic hybridization study of arsenic-exposed and non-arsenic-exposed urinary transitional cell carcinoma Fulltext Access 10 Pages 2008
Pharmacy stages of involvement in pharmacy-based immunization services: Results from a 17-state survey Fulltext Access 10 Pages 2008
Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin Fulltext Access 10 Pages 2008
Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity Fulltext Access 10 Pages 2008
Cobalt chloride attenuates hypobaric hypoxia induced vascular leakage in rat brain: Molecular mechanisms of action of cobalt chloride Fulltext Access 10 Pages 2008
Developmental exposure to trichloroethylene promotes CD4+ T cell differentiation and hyperactivity in association with oxidative stress and neurobehavioral deficits in MRL+/+ mice Fulltext Access 10 Pages 2008
Metallothionein-III protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a PI3K and ERK/Nrf2-dependent manner Fulltext Access 10 Pages 2008
Characterization of cadmium uptake and cytotoxicity in human osteoblast-like MG-63 cells Fulltext Access 10 Pages 2008
The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line Fulltext Access 10 Pages 2008