Convergent regulation of locus coeruleus activity as an adaptive response to stress Fulltext Access 10 Pages 2008
Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits Fulltext Access 10 Pages 2008
A novel selective peroxisome proliferator-activator receptor-γ modulator—SPPARγM5 improves insulin sensitivity with diminished adverse cardiovascular effects Fulltext Access 10 Pages 2008
Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-κB in RAW 264.7 macrophages Fulltext Access 10 Pages 2008
Tricyclic antidepressants inhibit homomeric Cys-loop receptors by acting at different conformational states Fulltext Access 10 Pages 2008
A dopamine mechanism is implied in the acquisition and expression of amphetamine and stress-induced effects observed in the lymphocyte subpopulations Fulltext Access 10 Pages 2008
Synergistic effects of chronic bryostatin-1 and α-tocopherol on spatial learning and memory in rats Fulltext Access 10 Pages 2008
Using pharmacokinetic–pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics Fulltext Access 10 Pages 2008
Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP Fulltext Access 10 Pages 2008
Isoliquiritigenin, a flavonoid from licorice, relaxes guinea-pig tracheal smooth muscle in vitro and in vivo: Role of cGMP/PKG pathway Fulltext Access 10 Pages 2008
Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells Fulltext Access 10 Pages 2008
Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-κB, JNK and p38 MAPK inactivation Fulltext Access 10 Pages 2008
Protective effect of bicyclol on acute alcohol-induced liver injury in mice Fulltext Access 10 Pages 2008
Anti-thrombotic and vascular effects of AR246686, a novel 5-HT2A receptor antagonist Fulltext Access 10 Pages 2008
Acute and chronic heroin dependence in mice: Contribution of opioid and excitatory amino acid receptors Fulltext Access 10 Pages 2008
Ginsenoside Rg1 protects neurons from hypoxic–ischemic injury possibly by inhibiting Ca2+ influx through NMDA receptors and L-type voltage-dependent Ca2+ channels Fulltext Access 10 Pages 2008
Rapid effects of 1α,25(OH)2D3 in resting human peripheral blood mononuclear cells Fulltext Access 10 Pages 2008
Diabetes-, stress- and ageing-related changes in synaptic plasticity in hippocampus and neocortex — The same metaplastic process? Fulltext Access 10 Pages 2008
Amyloid flirting with synaptic failure: Towards a comprehensive view of Alzheimer's disease pathogenesis Fulltext Access 10 Pages 2008
The use of the hippocampal slice preparation in the study of Alzheimer's disease Fulltext Access 10 Pages 2008
Increased adiposity on normal diet, but decreased susceptibility to diet-induced obesity in μ-opioid receptor-deficient mice Fulltext Access 10 Pages 2008
Myogenic tone and reactivity of cerebral arteries in Type II diabetic BBZDR/Wor rat Fulltext Access 10 Pages 2008
6,7-di-O-glucopyranosyl-esculetin protects SH-SY5Y cells from dopamine-induced cytotoxicity Fulltext Access 10 Pages 2008
Characterization of the α1-adrenoceptor subtype activating extracellular signal-regulated kinase in submandibular gland acinar cells Fulltext Access 10 Pages 2008
Protective effects of 2,3,5,4′-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice Fulltext Access 10 Pages 2008
Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse Fulltext Access 10 Pages 2008
Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice: Effect of intratracheal treatment of fluticasone propionate Fulltext Access 10 Pages 2008
Phosphorylation, desensitization and internalization of human α1B-adrenoceptors induced by insulin-like growth factor-I Fulltext Access 10 Pages 2008
Therapeutic resistance to angiotensin converting enzyme (ACE) inhibition is related to pharmacodynamic and -kinetic factors in 5/6 nephrectomized rats Fulltext Access 10 Pages 2008
Differential effects of the sodium calcium exchange inhibitor, KB-R7943, on ischemia and reperfusion injury in isolated guinea pig ventricular myocytes Fulltext Access 10 Pages 2008
The effect of intraperitoneal administration of leptin on short-term food intake in rats Fulltext Access 10 Pages 2008
Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-κB and Akt pathways Fulltext Access 10 Pages 2008
Cardiovascular effects of tyramine: Adrenergic and cholinergic interactions Fulltext Access 10 Pages 2008
Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors Fulltext Access 10 Pages 2008
Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents Fulltext Access 10 Pages 2008
Role of dopamine D3 receptors in the expression of conditioned fear in rats Fulltext Access 10 Pages 2008
Effects of chronic desipramine treatment on α2-adrenoceptors and μ-opioid receptors in the guinea pig cortex and hippocampus Fulltext Access 10 Pages 2008
Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts Fulltext Access 10 Pages 2008
Formulated antidiabetic preparation Syndrex® has a strong antioxidant activity Fulltext Access 10 Pages 2008
Role of K+ and Ca2+ fluxes in the cerebroarterial vasoactive effects of sildenafil Fulltext Access 10 Pages 2008
Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors Fulltext Access 10 Pages 2008
Antipsychotics differ in their ability to internalise human dopamine D2S and human serotonin 5-HT1A receptors in HEK293 cells Fulltext Access 10 Pages 2008
Morphine sex-dependently induced place conditioning in adult Wistar rats Fulltext Access 10 Pages 2008
Regulation of intracellular dopamine levels by dopaminergic drugs: Involvement of vesicular monoamine transporter Fulltext Access 10 Pages 2008
Volatile anesthetics and endogenous cannabinoid anandamide have additive and independent inhibitory effects on α7-nicotinic acetylcholine receptor-mediated responses in Xenopus oocytes Fulltext Access 10 Pages 2008
Identification and mapping of a region on the mRNA of Morbillivirus nucleoprotein susceptible to RNA interference Fulltext Access 10 Pages 2008
Paraquat inhibits postsynaptic AMPA receptors on dopaminergic neurons in the substantia nigra pars compacta Fulltext Access 10 Pages 2008
Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine Fulltext Access 10 Pages 2008
DNA damage and homologous recombination signaling induced by thymidylate deprivation Fulltext Access 10 Pages 2008
Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor Fulltext Access 10 Pages 2008
Glucocorticoid and mineralocorticoid action: Why should we consider influences by environmental chemicals? Fulltext Access 10 Pages 2008
Prophylactic and therapeutic intervention of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with interferon alfacon-1 Fulltext Access 10 Pages 2008
Does antiviral therapy have a role in the control of Japanese encephalitis? Fulltext Access 10 Pages 2008
Animal models of highly pathogenic RNA viral infections: Encephalitis viruses Fulltext Access 10 Pages 2008
Expression of the human cytomegalovirus UL97 gene in a chimeric guinea pig cytomegalovirus (GPCMV) results in viable virus with increased susceptibility to ganciclovir and maribavir Fulltext Access 10 Pages 2008
Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants Fulltext Access 10 Pages 2008
Therapeutic potential of a fully human monoclonal antibody against influenza A virus M2 protein Fulltext Access 10 Pages 2008
Interaction between the aryl hydrocarbon receptor and transforming growth factor-β signaling pathways: Evidence of an asymmetrical relationship in rat granulosa cells Fulltext Access 10 Pages 2008
Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach Fulltext Access 10 Pages 2008
Specific small interfering RNAs-mediated inhibition of replication of porcine encephalomyocarditis virus in BHK-21 cells Fulltext Access 10 Pages 2008
A scintillation proximity assay for dengue virus NS5 2′-O-methyltransferase—kinetic and inhibition analyses Fulltext Access 10 Pages 2008
Use/misuse of over-the-counter medications and associated adverse drug events among HIV-infected patients Fulltext Access 10 Pages 2008
“I just don't know what I'm supposed to know”: Evaluating self-assessment skills of international pharmacy graduates in Canada Fulltext Access 10 Pages 2008
Phytochemical composition and in vitro pharmacological activity of two rose hip (Rosa canina L.) preparations Fulltext Access 10 Pages 2008
Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE) Fulltext Access 10 Pages 2008
Regulative effects of essential oil from Atractylodes lancea on delayed gastric emptying in stress-induced rats Fulltext Access 10 Pages 2008
Possible nitric oxide modulation in protective effect of (Curcuma longa, Zingiberaceae) against sleep deprivation-induced behavioral alterations and oxidative damage in mice Fulltext Access 10 Pages 2008
Pharmacological characterization of RWJ-676070, a dual vasopressin V1A/V2 receptor antagonist Fulltext Access 10 Pages 2008
Octacosanol isolated from Tinospora cordifolia downregulates VEGF gene expression by inhibiting nuclear translocation of NF-<kappa>B and its DNA binding activity Fulltext Access 10 Pages 2008
Implications of ABC transporters on the disposition of typical veterinary medicinal products Fulltext Access 10 Pages 2008
Corticosteroid receptor-gene variants: Modulators of the stress-response and implications for mental health Fulltext Access 10 Pages 2008
Neuropharmacology of glucocorticoids: Focus on emotion, cognition and cocaine Fulltext Access 10 Pages 2008
Translational research into sexual disorders: Pharmacology and genomics Fulltext Access 10 Pages 2008
Angiotensin-(1–7): Pharmacological properties and pharmacotherapeutic perspectives Fulltext Access 10 Pages 2008
Paeonol inhibits RANKL-induced osteoclastogenesis by inhibiting ERK, p38 and NF-κB pathway Fulltext Access 10 Pages 2008
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney Fulltext Access 10 Pages 2008
Eckol protects V79-4 lung fibroblast cells against γ-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH2-terminal kinase pathway Fulltext Access 10 Pages 2008
Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway Fulltext Access 10 Pages 2008
Effect of seabuckthorn leaf extracts on circulating energy fuels, lipid peroxidation and antioxidant parameters in rats during exposure to cold, hypoxia and restraint (C–H–R) stress and post stress recovery Fulltext Access 10 Pages 2008
Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135) Fulltext Access 10 Pages 2008
Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue — Interactions with insulin Fulltext Access 10 Pages 2008
Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib Fulltext Access 10 Pages 2008
Activation of protein kinase C enhances NMDA-induced currents in primary cultured cerebellar granule cells: Effect of temperature and NMDA NR2 subunit composition Fulltext Access 10 Pages 2008
Supplementation with antioxidants fails to increase the total antioxidant capacity of several cell lines in culture Fulltext Access 10 Pages 2008
Exploration of associations between phospholipase A2 gene family polymorphisms and AIDS progression using the SNPlex™ method Fulltext Access 10 Pages 2008
Drug targeting of airway surface liquid: A pharmacological MRI approach Fulltext Access 10 Pages 2008
Regulation of liver cytochrome P450 by activation of brain dopaminergic system: Physiological and pharmacological implications Fulltext Access 10 Pages 2008
Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: The role of p53 and p21 Fulltext Access 10 Pages 2008
The cytostatic activity of pyrimidine nucleosides is strongly modulated by Mycoplasma hyorhinis infection: Implications for cancer therapy Fulltext Access 10 Pages 2008
Validating the mitotic kinesin Eg5 as a therapeutic target in pancreatic cancer cells and tumor xenografts using a specific inhibitor Fulltext Access 10 Pages 2008