CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon Fulltext Access 9 Pages 2007
Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes Fulltext Access 9 Pages 2007
Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary Fulltext Access 9 Pages 2007
Arginine vasopressin increases iNOS–NO system activity in cardiac fibroblasts through NF-κB activation and its relation with myocardial fibrosis Fulltext Access 9 Pages 2007
Nicotine's attenuation of body weight involves the perifornical hypothalamus Fulltext Access 9 Pages 2007
Effects of naturally occurring dihydroflavonols from Inula viscosa on inflammation and enzymes involved in the arachidonic acid metabolism Fulltext Access 9 Pages 2007
The amiodarone derivative 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015) opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle Fulltext Access 9 Pages 2007
Ethanol-induced dopamine elevation in the rat — Modulatory effects by subchronic treatment with nicotinic drugs Fulltext Access 9 Pages 2007
Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains Fulltext Access 9 Pages 2007
The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells Fulltext Access 9 Pages 2007
Mechanism underlying H2O2-induced inhibition of acetylcholine-induced contraction in rabbit tracheal smooth muscle Fulltext Access 9 Pages 2007
Enhanced G-protein coupled receptors-mediated contraction and reduced endothelium-dependent relaxation in hypertension Fulltext Access 9 Pages 2007
Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity Fulltext Access 9 Pages 2007
Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2 Fulltext Access 9 Pages 2007
Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons Fulltext Access 9 Pages 2007
In vitro electrophysiological mechanisms for antiarrhythmic efficacy of resveratrol, a red wine antioxidant Fulltext Access 9 Pages 2007
Antidepressant-induced undesirable weight gain: Prevention with rimonabant without interference with behavioral effectiveness Fulltext Access 9 Pages 2007
Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism Fulltext Access 9 Pages 2007
Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats Fulltext Access 9 Pages 2007
Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis Fulltext Access 9 Pages 2007
Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cells Fulltext Access 9 Pages 2007
Acid-induced modulation of airway basal tone and contractility: Role of acid-sensing ion channels (ASICs) and TRPV1 receptor Fulltext Access 9 Pages 2007
Effects of anethole and structural analogues on the contractility of rat isolated aorta: Involvement of voltage-dependent Ca2+-channels Fulltext Access 9 Pages 2007
Implication of cytosolic phospholipase A2 (cPLA2) in the regulation of human synoviocyte NADPH oxidase (Nox2) activity Fulltext Access 9 Pages 2007
Theanine, r-glutamylethylamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation Fulltext Access 9 Pages 2007
Butein blocks tumor necrosis factor α-induced interleukin 8 and matrix metalloproteinase 7 production by inhibiting p38 kinase and osteopontin mediated signaling events in HT-29 cells Fulltext Access 9 Pages 2007
Adenosine deaminase-related genes: Molecular identification, tissue expression pattern and truncated alternative splice isoform in adult zebrafish (Danio rerio) Fulltext Access 9 Pages 2007
Lycopene inhibits PDGF-BB-induced signaling and migration in human dermal fibroblasts through interaction with PDGF-BB Fulltext Access 9 Pages 2007
Activation of μ-opioid receptors improves insulin sensitivity in obese Zucker rats Fulltext Access 9 Pages 2007
Direct, real-time, simultaneous monitoring of intravitreal nitric oxide and oxygen in endotoxin-induced uveitis in rabbits Fulltext Access 9 Pages 2007
Chitosan nanoparticle as gene therapy vector via gastrointestinal mucosa administration: Results of an in vitro and in vivo study Fulltext Access 9 Pages 2007
Quetiapine attenuates spatial memory impairment and hippocampal neurodegeneration induced by bilateral common carotid artery occlusion in mice Fulltext Access 9 Pages 2007
Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2 expressions in arthritic mouse liver Fulltext Access 9 Pages 2007
Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes Fulltext Access 9 Pages 2007
NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase inhibitor, improves reduced walking distance and lowered hindlimb plantar surface temperature in a rat experimental intermittent claudication model Fulltext Access 9 Pages 2007
Effect of β-adrenergic and renin–angiotensin system blockade on myocyte apoptosis and oxidative stress in diabetic hypertensive rats Fulltext Access 9 Pages 2007
The cholinergic system is involved in regulation of the development of the hematopoietic system Fulltext Access 9 Pages 2007
Prenatal stress on the kinetic properties of Ca2+ and K+ channels in offspring hippocampal CA3 pyramidal neurons Fulltext Access 9 Pages 2007
Ischemia/reperfusion in rat heart induces leptin and leptin receptor gene expression Fulltext Access 9 Pages 2007
Cytoprotective and antioxidant role of diallyl tetrasulfide on cadmium induced renal injury: An in vivo and in vitro study Fulltext Access 9 Pages 2007
Excessive nitric oxide attenuates leptin-mediated signal transducer and activator of transcription 3 activation Fulltext Access 9 Pages 2007
Glucose-regulated insulin production from genetically engineered human non-beta cells Fulltext Access 9 Pages 2007
Theaflavins induce G2/M arrest by modulating expression of p21waf1/cip1, cdc25C and cyclin B in human prostate carcinoma PC-3 cells Fulltext Access 9 Pages 2007
Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters Fulltext Access 9 Pages 2007
Mechanisms of the antispasmodic activity of 3,5-di-t-butyl catechol (DTCAT) on rat vascular smooth muscles Fulltext Access 9 Pages 2007
Treatment with the xanthine oxidase inhibitor, allopurinol, improves nerve and vascular function in diabetic rats Fulltext Access 9 Pages 2007
Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood–brain barrier damage Fulltext Access 9 Pages 2007
S18986: A positive modulator of AMPA-receptors enhances (S)-AMPA-mediated BDNF mRNA and protein expression in rat primary cortical neuronal cultures Fulltext Access 9 Pages 2007
Role of reverse mode Na+/Ca2+ exchanger in the cardioprotection of metabolic inhibition preconditioning in rat ventricular myocytes Fulltext Access 9 Pages 2007
Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: Inhibition of cytokine production-dependent mechanism Fulltext Access 9 Pages 2007
YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models Fulltext Access 9 Pages 2007
Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species Fulltext Access 9 Pages 2007
Transforming growth factor-β1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-κB pathways in human lung epithelial cells Fulltext Access 9 Pages 2007
Probiotic Lactobacillus rhamnosus GG enhances gastric ulcer healing in rats Fulltext Access 9 Pages 2007
Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats Fulltext Access 9 Pages 2007
Regulator of G protein signaling proteins differentially modulate signaling of μ and δ opioid receptors Fulltext Access 9 Pages 2007
The role of gender and sex hormones in ischemic–reperfusion injury in isolated rat hearts Fulltext Access 9 Pages 2007
Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro Fulltext Access 9 Pages 2007
The importance of genetic background on pain behaviours and pharmacological sensitivity in the rat spared serve injury model of peripheral neuropathic pain Fulltext Access 9 Pages 2007
Adrenal adrenaline- and noradrenaline-containing cells and celiac sympathetic ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine–vasopressin in rats Fulltext Access 9 Pages 2007
Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease Fulltext Access 9 Pages 2007
The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Δ9-tetrahydrocannabinol in cultured cortical neurons Fulltext Access 9 Pages 2007
Mitochondria, ciglitazone and liver: A neglected interaction in biochemical pharmacology Fulltext Access 9 Pages 2007
Changes in ultrastructure and endogenous ionic channels activity during culture of HEK 293 cell line Fulltext Access 9 Pages 2007
Allosteric effects of R- and S-citalopram on the human 5-HT transporter: Evidence for distinct high- and low-affinity binding sites Fulltext Access 9 Pages 2007
Influence of cisplatin-induced renal failure on the α1-adrenoceptor subtype causing vasoconstriction in the kidney of the rat Fulltext Access 9 Pages 2007
Hyperbaric oxygen improves survival in heatstroke rats by reducing multiorgan dysfunction and brain oxidative stress Fulltext Access 9 Pages 2007
Role of TGF-β1 in vascular smooth muscle cell apoptosis induced by Angiotensin II Fulltext Access 9 Pages 2007
Anti-inflammatory activities of ent-16αH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-κB inactivation Fulltext Access 9 Pages 2007
Oral treatment with probucol in a pharmacological dose has no beneficial effects on mortality in chronic ischemic heart failure after large myocardial infarction in rats Fulltext Access 9 Pages 2007
Behavioral effects of the R-(+)- and S-(−)-enantiomers of the dopamine D1-like partial receptor agonist SKF 83959 in monkeys Fulltext Access 9 Pages 2007
Cordycepin (3′-deoxyadenosine) inhibits human platelet aggregation in a cyclic AMP- and cyclic GMP-dependent manner Fulltext Access 9 Pages 2007
Participation of CGRP and prostanoids in the sex-linked differences of vascular anandamide effects in mesenteric beds of Sprague-Dawley rats Fulltext Access 9 Pages 2007
Cilostazol, a phosphodiesterase 3 inhibitor, protects mice against acute and late ischemic brain injuries Fulltext Access 9 Pages 2007
Serotonin in microdialysate from the mediobasal hypothalamus increases after progesterone administration to estrogen primed macaques Fulltext Access 9 Pages 2007
Cloning and expression of canine glucagon receptor and its use to evaluate glucagon receptor antagonists in vitro and in vivo Fulltext Access 9 Pages 2007
Inhibitory effect of obovatol on nitric oxide production and activation of NF-κB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells Fulltext Access 9 Pages 2007
Peroxisome proliferator-activated receptor α-independent effects of peroxisome proliferators on cysteinyl leukotriene production in mast cells Fulltext Access 9 Pages 2007
Involvement of TRPV1-dependent and -independent components in the regulation of vagally induced contractions in the mouse esophagus Fulltext Access 9 Pages 2007
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain Fulltext Access 9 Pages 2007
Protective effect of Umbelliferone on membranous fatty acid composition in streptozotocin-induced diabetic rats Fulltext Access 9 Pages 2007
Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants Fulltext Access 9 Pages 2007
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene α-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate Fulltext Access 9 Pages 2007
Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation Fulltext Access 9 Pages 2007
Bakuchiol-induced caspase-3-dependent apoptosis occurs through c-Jun NH2-terminal kinase-mediated mitochondrial translocation of Bax in rat liver myofibroblasts Fulltext Access 9 Pages 2007
Vasopressin promotes cardiomyocyte hypertrophy via the vasopressin V1A receptor in neonatal mice Fulltext Access 9 Pages 2007
Novel neuroprotective compound SCH-20148 rescues thymocytes and SH-SY5Y cells from thapsigargin-induced mitochondrial membrane potential reduction and cell death Fulltext Access 9 Pages 2007
Potentiation of adrenaline vasoconstrictor response by sub-threshold concentrations of U-46619 in human umbilical vein: Involvement of smooth muscle prostanoid TPα receptor isoform Fulltext Access 9 Pages 2007
Post-training intrahippocampal infusion of nicotine–bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats Fulltext Access 9 Pages 2007
Omapatrilat enhances adrenomedullin's reduction of cardiomyocyte cell death Fulltext Access 9 Pages 2007
Functional activation by central monoamines of human dopamine D4 receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes Fulltext Access 9 Pages 2007