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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

The Ginkgo biloba extract EGb761 reduces stress sensitivity, ROS accumulation and expression of catalase and glutathione S-transferase 4 in Caenorhabditis elegans
Fulltext Access 9 Pages 2007
Effects of chlorpromazine on plasma membrane permeability and fluidity in the rat brain: A dynamic positron autoradiography and fluorescence polarization study
Fulltext Access 9 Pages 2007
Transient hypolocomotion in rats repeatedly exposed to phencyclidine: An appraisal of motor function and motivation
Fulltext Access 9 Pages 2007
Effectiveness and safety of olanzapine in the treatment of schizophrenia among Asian patients switching from conventional antipsychotics
Fulltext Access 9 Pages 2007
Activity-dependent neuroprotective protein: From gene to drug candidate
Fulltext Access 9 Pages 2007
The importance of cytochrome P450 2B6 in the human metabolism of environmental chemicals
Fulltext Access 9 Pages 2007
Manganese neurotoxicity: A focus on the neonate
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l-Arginine transporters in cardiovascular disease: A novel therapeutic target
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Cytochrome P450-catalyzed pathways in human brain: Metabolism meets pharmacology or old drugs with new mechanism of action?
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Pharmacology of N-desmethylclozapine
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Allosteric properties of G protein-coupled receptor oligomers
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Therapy of pulmonary hypertension in neonates and infants
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Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain
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Rewarding effects of 3,4-methylenedioxymethamphetamine (“Ecstasy”) in dominant and subordinate OF-1 mice in the place preference conditioning paradigm
Fulltext Access 9 Pages 2007
Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype
Fulltext Access 9 Pages 2007
Inhibition of extracellular signal-regulated kinase (ERK1/2) activity reverses endotoxin-induced hypotension via decreased nitric oxide production in rats
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Cytoprotective effect of preparations from various parts of Punica granatum L. fruits in oxidatively injured mammalian cells in comparison with their antioxidant capacity in cell free systems
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Berberine suppresses inflammatory agents-induced interleukin-1β and tumor necrosis factor-α productions via the inhibition of IκB degradation in human lung cells
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The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo
Fulltext Access 9 Pages 2007
Preference for palatable food is reduced by the gamma-hydroxybutyrate analogue GET73, in rats
Fulltext Access 9 Pages 2007
Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats
Fulltext Access 9 Pages 2007
Microarray analysis of vanillin-regulated gene expression profile in human hepatocarcinoma cells
Fulltext Access 9 Pages 2007
Adiponectin circulating levels: A new emerging biomarker of cardiovascular risk
Fulltext Access 9 Pages 2007
Growth-active peptides are produced from α-lactalbumin and lysozyme
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The potentiation of curcumin on insulin-like growth factor-1 action in MCF-7 human breast carcinoma cells
Fulltext Access 9 Pages 2007
Polygonum cuspidatum, compared with baicalin and berberine, inhibits inducible nitric oxide synthase and cyclooxygenase-2 gene expressions in RAW 264.7 macrophages
Fulltext Access 9 Pages 2007
Pharmacology under the microscope: the use of fluorescence correlation spectroscopy to determine the properties of ligand-receptor complexes
Fulltext Access 9 Pages 2007
Direct modulation of Ca2+-activated K+ current by H-89 in rabbit coronary arterial smooth muscle cells
Fulltext Access 9 Pages 2007
Evidence supporting changes in Nogo-B levels as a marker of neointimal expansion but not adaptive arterial remodeling
Fulltext Access 9 Pages 2007
Involvement of endothelial cell-derived CGRP in heat stress-induced protection of endothelial function
Fulltext Access 9 Pages 2007
Endothelial injury in the initiation and progression of vascular disorders
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Pharmacological preconditioning by levosimendan is mediated by inducible nitric oxide synthase and mitochondrial KATP channel activation in the in vivo anesthetized rabbit heart model
Fulltext Access 9 Pages 2007
Epothilone D, a microtubule-stabilizing compound, inhibits neointimal hyperplasia after rat carotid artery injury by cell cycle arrest via regulation of G1-checkpoint proteins
Fulltext Access 9 Pages 2007
Changes in stretch-induced tone induced by intracellular acidosis in rabbit basilar artery: Effects on BKCa channel activity
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A modified fluorescent microsphere-based approach for determining resting and hyperemic blood flows in individual murine skeletal muscles
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Oxidized low density lipoprotein receptor-1 mediates oxidized low density lipoprotein-induced apoptosis in human umbilical vein endothelial cells: Role of reactive oxygen species
Fulltext Access 9 Pages 2007
Large scale analysis of genes contributing to the herbal preparation dependent hippocampal plasticity in postischemic rehabilitation
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Possible involvement of enhanced arginase activity due to up-regulated arginases and decreased hydroxyarginine in accelerating intimal hyperplasia with hyperglycemia
Fulltext Access 9 Pages 2007
Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG
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Alterations of intracellular calcium concentration and nitric oxide generation in pulmonary artery endothelium after subarachnoid hemorrhage of the rabbit
Fulltext Access 9 Pages 2007
Antiproliferative activity of NQ304, a synthetic 1,4-naphthoquinone, is mediated via the suppressions of the PI3K/Akt and ERK1/2 signaling pathways in PDGF-BB-stimulated vascular smooth muscle cells
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Statins and the endothelium
Fulltext Access 9 Pages 2007
Trafficking of δ-opioid receptors and other G-protein-coupled receptors: implications for pain and analgesia
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Exploring the pharmacological properties of insect nicotinic acetylcholine receptors
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Functional biology of the α2δ subunits of voltage-gated calcium channels
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Methylphenidate and cocaine: the same effects on gene regulation?
Fulltext Access 9 Pages 2007
Impaired pre-attentive auditory processing in opioid dependence with and without benzodiazepine co-dependence revealed by combined magnetoencephalography and electroencephalography
Fulltext Access 9 Pages 2007
Proline-rich polypeptides in Alzheimer's disease and neurodegenerative disorders — Therapeutic potential or a mirage?
Fulltext Access 9 Pages 2007
Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats
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Alterations of muscarinic and GABA receptor binding in the posterior cingulate cortex in schizophrenia
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The value added by measuring myocardial contractility ‘in vivo’ in safety pharmacological profiling of drug candidates
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Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients
Fulltext Access 9 Pages 2007
Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12- lipoxygenase activation in glioma cells
Fulltext Access 9 Pages 2007
Analogs of SR-141716A (Rimonabant) alter d-amphetamine-evoked [3H] dopamine overflow from preloaded striatal slices and amphetamine-induced hyperactivity
Fulltext Access 9 Pages 2007
Effects of leucine and phenylalanine supplementation during intermittent periods of food restriction and refeeding in adult rats
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Nifurtimox nitroreductase activity in different cellular fractions from male rat pancreas. Biochemical and ultrastructural alterations
Fulltext Access 9 Pages 2007
Reproductive experience modifies dopaminergic function, serum levels of prolactin, and macrophage activity in female rats
Fulltext Access 9 Pages 2007
Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins
Fulltext Access 9 Pages 2007
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line
Fulltext Access 9 Pages 2007
Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells
Fulltext Access 9 Pages 2007
Analysis of the nonclinical telemetered ECG: Impact of logging rate and RR bin width in the dog and cynomolgus monkey
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A panic experimental model: Validation of a complex operant behavioral method in undernourished rats, with desipramine to provide a template effect profile
Fulltext Access 9 Pages 2007
Pharmacokinetic comparisons of tail-bleeding with cannula- or retro-orbital bleeding techniques in rats using six marketed drugs
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Long-term d-galactose injection combined with ovariectomy serves as a new rodent model for Alzheimer's disease
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Towards automation of a valuable preclinical cardiac safety pharmacology assay: Evaluation of the effects of cardiac ion channel blockers on cardiac repolarisation in vitro
Fulltext Access 9 Pages 2007
A cardiovascular monitoring system used in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 2: Pharmacological validation
Fulltext Access 9 Pages 2007
Comparison of rat and dog models of vasodilatation and lipolysis for the calculation of a therapeutic index for GPR109A agonists
Fulltext Access 9 Pages 2007
A bladder-cooling reflex in the anaesthetised guinea-pig: A model of the positive clinical ice-water test
Fulltext Access 9 Pages 2007
Altered ion transport and responsiveness to methacholine and hyperosmolarity in air interface-cultured guinea-pig tracheal epithelium
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Comparison of the influence of NSAIDs with different COX-selectivity on histamine release from mast cells isolated from naïve and sensitized rats
Fulltext Access 9 Pages 2007
Modulation of immune response in mice immunised with an inactivated Salmonella vaccine and gavaged with Andrographis paniculata extract or andrographolide
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Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia
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Equol inhibits nitric oxide production and inducible nitric oxide synthase gene expression through down-regulating the activation of Akt
Fulltext Access 9 Pages 2007
Ovalbumin modified by gamma irradiation alters its immunological functions and allergic responses
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Protective effect of CpG-DNA against mastitis induced by Staphylococcus aureus infection in a rat model
Fulltext Access 9 Pages 2007
Role of nitric oxide/cyclic GMP/K+ channel pathways in the antinociceptive effect caused by 2,3-bis(mesitylseleno)propenol
Fulltext Access 9 Pages 2007
Augmented behavioral response and enhanced synaptosomal calcium transport induced by repeated cocaine administration are decreased by calcium channel blockers
Fulltext Access 9 Pages 2007
Testosterone deficiency impairs glucose oxidation through defective insulin and its receptor gene expression in target tissues of adult male rats
Fulltext Access 9 Pages 2007
Mechanism of ethanol enhancement of apoptosis and caspase activation in serum-deprived PC12 cells
Fulltext Access 9 Pages 2007
The regulatory effect of endogenous hydrogen sulfide on pulmonary vascular structure and gasotransmitters in rats with high pulmonary blood flow
Fulltext Access 9 Pages 2007
Icaritin and its glycosides enhance osteoblastic, but suppress osteoclastic, differentiation and activity in vitro
Fulltext Access 9 Pages 2007
Isoform-specific downregulation of peroxiredoxin in human failing myocardium
Fulltext Access 9 Pages 2007
Kinin B1 receptor participates in the control of cardiac function in mice
Fulltext Access 9 Pages 2007
Protease-activated receptor 4-mediated Ca2+ signaling in mouse lung alveolar epithelial cells
Fulltext Access 9 Pages 2007
Potential involvement of the cyclooxygenase-2 pathway in hepatocellular carcinoma-associated angiogenesis
Fulltext Access 9 Pages 2007
Carboxylesterase in the liver and small intestine of experimental animals and human
Fulltext Access 9 Pages 2007
Nucleotide metabolizing ecto-enzymes in Walker 256 tumor cells: Molecular identification, kinetic characterization and biochemical properties
Fulltext Access 9 Pages 2007
The influence of stress and methionine-enkephalin on macrophage functions in two inbred rat strains
Fulltext Access 9 Pages 2007
Experimental AA amyloidosis in mice is inhibited by treatment with triptolide, a purified traditional Chinese medicine
Fulltext Access 9 Pages 2007
Prostaglandin E2 and I2 facilitate noxious heat-induced spike discharge but not iCGRP release from rat cutaneous nociceptors
Fulltext Access 9 Pages 2007
Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats
Fulltext Access 9 Pages 2007
Induction of human sulfotransferase 1A3 (SULT1A3) by glucocorticoids
Fulltext Access 9 Pages 2007
Cardiomyocyte apoptosis in the right auricle of patients with ostium secundum atrial septal defect diseases
Fulltext Access 9 Pages 2007
Altered expression profiles of clock genes hPer1 and hPer2 in peripheral blood mononuclear cells of cancer patients undergoing surgery
Fulltext Access 9 Pages 2007
Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy
Fulltext Access 9 Pages 2007
ACTX-8, a cytotoxic l-amino acid oxidase isolated from Agkistrodon acutus snake venom, induces apoptosis in Hela cervical cancer cells
Fulltext Access 9 Pages 2007
Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms
Fulltext Access 9 Pages 2007
Hypertension aggravates glomerular dysfunction with oxidative stress in a rat model of diabetic nephropathy
Fulltext Access 9 Pages 2007
Inhibition by epigallocatechin gallate of CoCl2-induced apoptosis in rat PC12 cells
Fulltext Access 9 Pages 2007
Antioxidant responses and lipid peroxidation following intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats: increased susceptibility of olfactory bulb
Fulltext Access 9 Pages 2007
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