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Pharmacology Research Articles

A quantitative regional expression profile of EAAT2 known and novel splice variants reopens the question of aberrant EAAT2 splicing in disease
Fulltext Access 10 Pages 2007
In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver
Fulltext Access 10 Pages 2007
Effect of Moisture and Pressure on Tablet Compaction Studied With FTIR Spectroscopic Imaging
Fulltext Access 10 Pages 2007
Air-Liquid Interface (ALI) Culture of Human Bronchial Epithelial Cell Monolayers as an in vitro Model for Airway Drug Transport Studies
Fulltext Access 10 Pages 2007
Selectivity of Similar Compounds Identification Using IR Spectroscopy: Steroids
Fulltext Access 10 Pages 2007
Predicting Human Drug Pharmacokinetics from In Vitro Permeability Using an Absorption-Disposition Model
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Relative in Vitro Efficacy of the Phosphate Binders Lanthanum Carbonate and Sevelamer Hydrochloride
Fulltext Access 10 Pages 2007
Grapefruit Juice-Drug Interactions: Grapefruit Juice and Its Components Inhibit P‐Glycoprotein (ABCB1) Mediated Transport of Talinolol in Caco‐2 Cells
Fulltext Access 10 Pages 2007
In Vitro Penetration of a Novel Oxaborole Antifungal (AN2690) Into the Human Nail Plate
Fulltext Access 10 Pages 2007
Hypertension artérielle pulmonaire : stratégies de prise en charge
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Médicaments sous autorisation temporaire d'utilisation (ATU)
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Innovations thérapeutiques hors ATU
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Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1
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Modifying Drug Release and Tablet Properties of Starch Acetate Tablets by Dry Powder Agglomeration
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Pentosan polysulfate protects brain endothelial cells against bacterial lipopolysaccharide-induced damages
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Regulation of G proteins by human 5-HT1a receptor TM3/i2 and TM5/i3 loop peptides
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Presynaptic mechanisms underlying the α-lipoic acid facilitation of glutamate exocytosis in rat cerebral cortex nerve terminals
Fulltext Access 10 Pages 2007
Differential protein expression in the corpus callosum (splenium) of human alcoholics: A proteomics study
Fulltext Access 10 Pages 2007
A2A adenosine-receptor-mediated facilitation of noradrenaline release in rat tail artery involves protein kinase C activation and βγ subunits formed after α2-adrenoceptor activation
Fulltext Access 10 Pages 2007
Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: Implications in excitotoxicity
Fulltext Access 10 Pages 2007
The usefulness of the spontaneously hypertensive rat to model attention-deficit/hyperactivity disorder (ADHD) may be explained by the differential expression of dopamine-related genes in the brain
Fulltext Access 10 Pages 2007
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes
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Long-term kainic acid exposure reveals compartmentation of glutamate and glutamine metabolism in cultured cerebellar neurons
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Targeted stem cell transplantation strategies in ALS
Fulltext Access 10 Pages 2007
More than their sum in your parts: the mechanisms that underpin the mutually advantageous relationship between HIV and sexually transmitted infections
Fulltext Access 10 Pages 2007
Hydrates and Solid-State Reactivity: A Survey of β-Lactam Antibiotics
Fulltext Access 10 Pages 2007
Pain, problem drug use history, and aberrant analgesic use behaviors in persons living with HIV
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Engineering an endomorphin-2 gene for use in neuropathic pain therapy
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Investigation of Drying Stresses on Proteins during Lyophilization: Differentiation between Primary and Secondary-Drying Stresses on Lactate Dehydrogenase Using a Humidity Controlled Mini Freeze-Dryer
Fulltext Access 10 Pages 2007
Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Isoniazid*
Fulltext Access 10 Pages 2007
Species Differences of Inhibitory Effects on P‐glycoprotein‐mediateD Drug Transport
Fulltext Access 10 Pages 2007
Different HPMC Viscosity Grades as Coating Agents for an Oral Time and/or Site‐Controlled Delivery System: An Investigation into the Mechanisms Governing Drug Release
Fulltext Access 10 Pages 2007
Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Prednisone
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Ex Vivo Study of Transdermal Permeation of Four Diclofenac Salts from Different Vehicles
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Gelatin‐stabilised microemulsion‐based organogels facilitates percutaneous penetration of Cyclosporin A In Vitro and dermal pharmacokinetics In Vivo
Fulltext Access 10 Pages 2007
The 3-D model: Experimental Testing of the Parameters d, e, and ω and Validation of the Analysis
Fulltext Access 10 Pages 2007
Transformation of Pharmaceutical Compounds upon Milling and Comilling: The Role of Tg
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Process Analytical Technology: Chemometric Analysis of Raman and Near Infra-Red Spectroscopic Data for Predicting Physical Properties of Extended Release Matrix Tablets
Fulltext Access 10 Pages 2007
Progress in the discovery and development of glutamate carboxypeptidase II inhibitors
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Solvent Influences on Metastable Polymorph Lifetimes: Real-Time Interconversions Using Energy Dispersive X-Ray Diffractometry*
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Thermal Expansion of Organic Crystals and Precision of Calculated Crystal Density: A Survey of Cambridge Crystal Database
Fulltext Access 10 Pages 2007
Characterization of Prednisolone in Controlled Porosity Osmotic Pump Pellets using Solid-State NMR Spectroscopy
Fulltext Access 10 Pages 2007
Stability and degradation kinetics of etoposide‐loaded parenteral lipid emulsion
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Influence of crystal structure on the tableting properties of n‐alkyl 4‐hydroxybenzoate esters (parabens)
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A comparative study of the antigen‐specific immune response induced by co‐delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles*
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Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP)
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Onion Phases of PEG-8 Distearate
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Solid‐state properties and relationship between anhydrate and monohydrate of baclofen
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Single-Droplet Evaporation Kinetics and Particle Formation in an Acoustic Levitator. Part 1: Evaporation of Water Microdroplets Assessed Using Boundary-Layer and Acoustic Levitation Theories
Fulltext Access 10 Pages 2007
A Solid-State Chemist's View of the Crystal Polymorphism of Organic Compounds
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Behavioral and pharmacological description of oxaliplatin-induced painful neuropathy in rat
Fulltext Access 10 Pages 2007
A new lectin from the sea worm Serpula vermicularis: Isolation, characterization and anti-HIV activity
Fulltext Access 10 Pages 2007
Effects of copper and cadmium on cholinesterase and glutathione S-transferase activities of two marine gastropods (Monodonta lineata and Nucella lapillus)
Fulltext Access 10 Pages 2007
Endocrine modulating actions of a phytosterol mixture and its oxidation products in zebrafish (Danio rerio)
Fulltext Access 10 Pages 2007
Quantitative oral dosing of water soluble and lipophilic contaminants in the Japanese medaka (Oryzias latipes)
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Mycobacterium marinum produces long-term chronic infections in medaka: A new animal model for studying human tuberculosis
Fulltext Access 10 Pages 2007
DNA microarray technology in toxicogenomics of aquatic models: Methods and applications
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Egg carotenoproteins in neotropical Ampullariidae (Gastropoda: Arquitaenioglossa)
Fulltext Access 10 Pages 2007
NMDA receptor-mediated activation of medullary pro-nociceptive neurons is required for secondary thermal hyperalgesia
Fulltext Access 10 Pages 2007
Does sleep quality predict pain-related disability in chronic pain patients? The mediating roles of depression and pain severity
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Higher levels of pain readiness to change and more positive affect reduce pain reports – A weekly assessment study on arthritis patients
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Modality-specific sensory changes in humans after the induction of long-term potentiation (LTP) in cutaneous nociceptive pathways
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Defining the nociceptive flexion reflex (NFR) threshold in human participants: A comparison of different scoring criteria
Fulltext Access 10 Pages 2007
Benzo[a]pyrene up-regulates the expression of the proliferating cell nuclear antigen (PCNA) and multixenobiotic resistance polyglycoprotein (P-gp) in Baltic Sea blue mussels (Mytilus edulis L.)
Fulltext Access 10 Pages 2007
Spinal microglia and neuropathic pain in young rats
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Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both β2- and β3-adrenergic receptors
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Pulsed radiofrequency adjacent to the cervical dorsal root ganglion in chronic cervical radicular pain: A double blind sham controlled randomized clinical trial
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Analgesic action of gabapentin on chronic pain in the masticatory muscles: A randomized controlled trial
Fulltext Access 10 Pages 2007
Anti-allodynic effects of peripheral delta opioid receptors in neuropathic pain
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Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients
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Fear of movement/(re)injury in chronic pain: A psychometric assessment of the original English version of the Tampa scale for kinesiophobia (TSK)
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Amygdala GABA-A receptor involvement in mediating sensory-discriminative and affective-motivational pain responses in a rat model of peripheral nerve injury
Fulltext Access 10 Pages 2007
Interaction of psychosocial risk factors explain increased neck problems among female office workers
Fulltext Access 10 Pages 2007
Predictors of onset of facial pain and temporomandibular disorders in early adolescence
Fulltext Access 10 Pages 2007
Helplessness and loss as mediators between pain and depressive symptoms in fibromyalgia
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Antinociceptive effects of systemic paeoniflorin on bee venom-induced various ‘phenotypes’ of nociception and hypersensitivity
Fulltext Access 10 Pages 2007
Designing drugs for the treatment of female sexual dysfunction
Fulltext Access 10 Pages 2007
Support vector machines approach for predicting druggable proteins: recent progress in its exploration and investigation of its usefulness
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Communicating the risks and benefits of medicines
Fulltext Access 10 Pages 2007
In silico selection of active siRNA
Fulltext Access 10 Pages 2007
Identification of drugs that interact with herbs in drug development
Fulltext Access 10 Pages 2007
Panning for SNuRMs: using cofactor profiling for the rational discovery of selective nuclear receptor modulators
Fulltext Access 10 Pages 2007
Combined therapy for tuberculosis and HIV-1: the challenge for drug discovery
Fulltext Access 10 Pages 2007
Acute d-amphetamine pretreatment does not alter stimulant self-administration in humans
Fulltext Access 10 Pages 2007
Strain differences in the disruption of prepulse inhibition of startle after systemic and intra-accumbens amphetamine administration
Fulltext Access 10 Pages 2007
Co-administration of rofecoxib and tramadol results in additive or sub-additive interaction during arthritic nociception in rat
Fulltext Access 10 Pages 2007
d-Cycloserine enhances conditioned taste aversion learning in rats
Fulltext Access 10 Pages 2007
Electrophysiological responses to affective stimuli in Mexican Americans: Relationship to alcohol dependence and personality traits
Fulltext Access 10 Pages 2007
Pain among the oldest old in community and institutional settings
Fulltext Access 10 Pages 2007
Sex differences in (+)-amphetamine- and (+)-methamphetamine-induced behavioral response in male and female Sprague–Dawley rats
Fulltext Access 10 Pages 2007
Faster onset and dopamine transporter selectivity predict stimulant and reinforcing effects of cocaine analogs in squirrel monkeys
Fulltext Access 10 Pages 2007
NMDA receptor in conditioned flavor-taste preference learning: Blockade by MK-801 and enhancement by D-cycloserine
Fulltext Access 10 Pages 2007
Chronic buprenorphine reduces the response to sucrose-associated cues in non food-deprived rats
Fulltext Access 10 Pages 2007
Pharmacological evaluation of opioid and non-opioid analgesics in a murine bone cancer model of pain
Fulltext Access 10 Pages 2007
Comparison of the V1b antagonist, SSR149415, and the CRF1 antagonist, CP-154,526, in rodent models of anxiety and depression
Fulltext Access 10 Pages 2007
Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice
Fulltext Access 10 Pages 2007
7-Nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs passive-avoidance and elevated plus-maze memory performance in rats
Fulltext Access 10 Pages 2007
Serotonin decreases aggression via 5-HT1A receptors in the fighting fish Betta splendens
Fulltext Access 10 Pages 2007
MDMA-like behavioral effects of N-substituted piperazines in the mouse
Fulltext Access 10 Pages 2007
Estrogenic, anti-estrogenic and cytotoxic effects elicited by water from the type localities of the endangered goodeid fish Girardinichthys viviparus
Fulltext Access 10 Pages 2007
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