Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid Fulltext Access 10 Pages 2007
Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde⁎ Fulltext Access 10 Pages 2007
Chaperones are the target in aloe-emodin-induced human lung nonsmall carcinoma H460 cell apoptosis Fulltext Access 10 Pages 2007
Effects of the serotonin 5-HT2A and 5-HT2C receptor ligands on the discriminative stimulus effects of nicotine in rats Fulltext Access 10 Pages 2007
Zaprinast inhibits hydrogen peroxide-induced lysosomal destabilization and cell death in astrocytes Fulltext Access 10 Pages 2007
Effects of GABAB receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination Fulltext Access 10 Pages 2007
Piperine inhibits TNF-α induced adhesion of neutrophils to endothelial monolayer through suppression of NF-κB and IκB kinase activation Fulltext Access 10 Pages 2007
Study of plasma protein C and inflammatory pathways: Biomarkers for dimethylnitrosamine-induced liver fibrosis in rats Fulltext Access 10 Pages 2007
Anti-inflammatory activity of 21(α, β)-methylmelianodiols, novel compounds from Poncirus trifoliata Rafinesque Fulltext Access 10 Pages 2007
Mechanisms of relaxation by carbon monoxide-releasing molecule-2 in murine gastric fundus and jejunum Fulltext Access 10 Pages 2007
ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle Fulltext Access 10 Pages 2007
Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: Involvement of central oxytocin Fulltext Access 10 Pages 2007
The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke Fulltext Access 10 Pages 2007
Effects of phenylalkylamines and benzothiazepines on Cav1.3-mediated Ca2+ currents in neonatal mouse inner hair cells Fulltext Access 10 Pages 2007
Reversal of learned helplessness by selective serotonin reuptake inhibitors in rats is not dependent on 5-HT availability Fulltext Access 10 Pages 2007
Differences in kinetics of structurally related competitive GABAA receptor antagonists Fulltext Access 10 Pages 2007
The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task Fulltext Access 10 Pages 2007
Gaboxadol, a selective extrasynaptic GABAA agonist, does not generalise to other sleep-enhancing drugs: A rat drug discrimination study Fulltext Access 10 Pages 2007
Excitatory amino acid receptor-mediated responses in periaqueductal gray neurons are increased during ethanol withdrawal Fulltext Access 10 Pages 2007
Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activation Fulltext Access 10 Pages 2007
Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A2 by Aβ1–42 Fulltext Access 10 Pages 2007
Targeting the cholinergic system as a therapeutic strategy for the treatment of pain Fulltext Access 10 Pages 2007
Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression Fulltext Access 10 Pages 2007
Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: Correlated with NO–cGMP signaling pathway Fulltext Access 10 Pages 2007
Studies on the mechanisms underlying amiloride enhancement of 3,4-methylenedioxymethamphetamine-induced serotonin depletion in rats Fulltext Access 10 Pages 2007
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats Fulltext Access 10 Pages 2007
Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury in rats Fulltext Access 10 Pages 2007
Effects of the fatty acid amide hydrolase inhibitor URB597 on the sleep-wake cycle, c-Fos expression and dopamine levels of the rat Fulltext Access 10 Pages 2007
Nitrosothiol stores in vascular tissue: Modulation by ultraviolet light, acetylcholine and ionomycin Fulltext Access 10 Pages 2007
Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA Fulltext Access 10 Pages 2007
Inhibition of tolerance to spinal morphine antinociception by low doses of opioid receptor antagonists Fulltext Access 10 Pages 2007
Contribution of Ca2+ influx to carbachol-induced detrusor contraction is different in human urinary bladder compared to pig and mouse Fulltext Access 10 Pages 2007
Adenoviral-mediated expression of dihydropyridine-insensitive L-type calcium channels in cardiac ventricular myocytes and fibroblasts Fulltext Access 10 Pages 2007
Antioxidant effect of erythropoietin on 1-methyl-4-phenylpyridinium-induced neurotoxicity in PC12 cells Fulltext Access 10 Pages 2007
Direct adipotropic actions of atorvastatin: Differentiation state-dependent induction of apoptosis, modulation of endocrine function, and inhibition of glucose uptake Fulltext Access 10 Pages 2007
Clinical efficacy of buprenorphine to minimize distress in MRL/lpr mice Fulltext Access 10 Pages 2007
Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo Fulltext Access 10 Pages 2007
Ethanolamine and related amino alcohols increase basal and evoked release of [3H]-d-aspartic acid from synaptosomes by enhancing the filling of synaptic vesicles Fulltext Access 10 Pages 2007
Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells Fulltext Access 10 Pages 2007
Modification of alterations in cardiac function and sarcoplasmic reticulum by astragaloside IV in myocardial injury in vivo Fulltext Access 10 Pages 2007
Reorganization of dorsal root ganglion neurons following chronic sciatic nerve constriction injury: Correlation with morphine and lidocaine analgesia Fulltext Access 10 Pages 2007
Multiple mechanisms underlying the anticancer action of nanocrystalline fullerene Fulltext Access 10 Pages 2007
Cooling augments vasoconstriction mediated by 5-HT1 and α2-adrenoceptors in the isolated equine digital vein: involvement of Rho kinase Fulltext Access 10 Pages 2007
Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expression Fulltext Access 10 Pages 2007
Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension Fulltext Access 10 Pages 2007
Probucol mediates vascular remodeling after percutaneous transluminal angioplasty via down-regulation of the ERK1/2 signaling pathway Fulltext Access 10 Pages 2007
NCX 6560, a nitric oxide-releasing derivative of atorvastatin, inhibits cholesterol biosynthesis and shows anti-inflammatory and anti-thrombotic properties Fulltext Access 10 Pages 2007
Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice Fulltext Access 10 Pages 2007
Neuroprotection conferred by astrocytes is insufficient to protect animals from succumbing to Japanese encephalitis Fulltext Access 10 Pages 2007
Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone Fulltext Access 10 Pages 2007
Different effects of ionotropic and metabotropic glutamate receptor antagonists on attention and the attentional properties of nicotine Fulltext Access 10 Pages 2007
Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex Fulltext Access 10 Pages 2007
Sustained increase of alpha7 nicotinic receptors and choline-induced improvement of learning deficit in STOP knock-out mice Fulltext Access 10 Pages 2007
Presynaptic AMPA and kainate receptors increase the size of GABAergic terminals and enhance GABA release Fulltext Access 10 Pages 2007
Identification of residues mediating inhibition of glycine receptors by protons Fulltext Access 10 Pages 2007
Voltammetric characterization of the effect of monoamine uptake inhibitors and releasers on dopamine and serotonin uptake in mouse caudate-putamen and substantia nigra slices Fulltext Access 10 Pages 2007
Glycine-induced long-term synaptic potentiation is mediated by the glycine transporter GLYT1 Fulltext Access 10 Pages 2007
Blockade of GABAA receptors within the extended amygdala attenuates D2 regulation of alcohol-motivated behaviors in the ventral tegmental area of alcohol-preferring (P) rats Fulltext Access 10 Pages 2007
A spinal muscarinic M2 receptor-GABAergic disinhibition pathway that modulates peripheral inflammation in mice Fulltext Access 10 Pages 2007
Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety Fulltext Access 10 Pages 2007
Implication of PTEN in production of reactive oxygen species and neuronal death in in vitro models of stroke and Parkinson's disease Fulltext Access 10 Pages 2007
NMDA inhibitors cause apoptosis of pyramidal neurons in mature piriform cortex: Evidence for a nitric oxide-mediated effect involving inhibitory interneurons Fulltext Access 10 Pages 2007
Comparison of [3H]-(2S,4R)-4-methylglutamate and [3H]d-aspartate as ligands for binding and autoradiographic analyses of glutamate transporters Fulltext Access 10 Pages 2007
Acute flesinoxan treatment produces a different effect on rat brain serotonin synthesis than chronic treatment: An α-methyl-l-tryptophan autoradiographic study Fulltext Access 10 Pages 2007
S1P-receptors in PC12 and transfected HEK293 cells: Molecular targets of hypotensive imidazoline I1 receptor ligands Fulltext Access 10 Pages 2007
Altered glutathione homeostasis in animals prenatally exposed to lipopolysaccharide Fulltext Access 10 Pages 2007
Copper and zinc as modulators of neuronal excitability in a physiologically significant concentration range Fulltext Access 10 Pages 2007
Biochemical analysis of ecto-nucleotide pyrophosphatase phosphodiesterase activity in brain membranes indicates involvement of NPP1 isoenzyme in extracellular hydrolysis of diadenosine polyphosphates in central nervous system Fulltext Access 10 Pages 2007
Cystic fibrosis: the mechanisms of pathogenesis of an inherited lung disorder Fulltext Access 10 Pages 2007
Ischemic preconditioning and myocardial infarction: An update and perspective Fulltext Access 10 Pages 2007
The lysosome or lysosome-related organelle may serve as a Ca2+ store in the boutons of hippocampal pyramidal cells Fulltext Access 10 Pages 2007
Valerenic acid potentiates and inhibits GABAA receptors: Molecular mechanism and subunit specificity Fulltext Access 10 Pages 2007
Involvement of nitric oxide in the inhibition of bone cancer-induced hyperalgesia through the activation of peripheral opioid receptors in mice Fulltext Access 10 Pages 2007
Peripheral kinin B1 and B2 receptor-operated mechanisms are implicated in neuropathic nociception induced by spinal nerve ligation in rats Fulltext Access 10 Pages 2007
Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus Fulltext Access 10 Pages 2007
Akt-dependent heme oxygenase-1 induction by NS-398 in C6 glial cells: A potential role for CO in prevention of oxidative damage from hypoxia Fulltext Access 10 Pages 2007
Model-specific effects of bumetanide on epileptiform activity in the in-vitro intact hippocampus of the newborn mouse Fulltext Access 10 Pages 2007
Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons Fulltext Access 10 Pages 2007
Involvement of brain endogenous histamine in the degeneration of dopaminergic neurons in 6-hydroxydopamine-lesioned rats Fulltext Access 10 Pages 2007
Dendritic calcium spikes induce bi-directional synaptic plasticity in the lateral amygdala Fulltext Access 10 Pages 2007
GABAA receptor-associated phosphoinositide 3-kinase is required for insulin-induced recruitment of postsynaptic GABAA receptors Fulltext Access 10 Pages 2007
The HMG-CoA reductase inhibitor, atorvastatin, attenuates the effects of acute administration of amyloid-β1–42 in the rat hippocampus in vivo Fulltext Access 10 Pages 2007
mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082 Fulltext Access 10 Pages 2007
The role of NMDAR subtypes and charge transfer during hippocampal LTP induction Fulltext Access 10 Pages 2007
Tyramine excites rat subthalamic neurons in vitro by a dopamine-dependent mechanism Fulltext Access 10 Pages 2007
The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice Fulltext Access 10 Pages 2007
5-HT3 receptor-mediated photic-like responses of the circadian clock in the rat Fulltext Access 10 Pages 2007
Dopamine selectively potentiates hippocampal mossy fiber to CA3 synaptic transmission Fulltext Access 10 Pages 2007
Galantamine and donepezil attenuate pharmacologically induced deficits in prepulse inhibition in rats Fulltext Access 10 Pages 2007
Evidence for adenosine- and serotonin-mediated antihyperalgesic effects of cizolirtine in rats suffering from diabetic neuropathy Fulltext Access 10 Pages 2007
Effects of amphetamine isomers, methylphenidate and atomoxetine on synaptosomal and synaptic vesicle accumulation and release of dopamine and noradrenaline in vitro in the rat brain Fulltext Access 10 Pages 2007
In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: Evidence for two distinct I2 binding sites Fulltext Access 10 Pages 2007
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice Fulltext Access 10 Pages 2007