Structure and Drug Release in a Crosslinked Poly(Ethylene Oxide) Hydrogel Fulltext Access 11 Pages 2007
Biowaiver Monographs for Immediate Release Solid OralDosage Forms: Prednisolone Fulltext Access 11 Pages 2007
Influence of Polymorphic Form, Morphology, and Excipient Interactions on the Dissolution of Carbamazepine Compacts Fulltext Access 11 Pages 2007
Neuroprotection of Retinal Ganglion Cells in DBA/2J Mice With GDNF-Loaded Biodegradable Microspheres Fulltext Access 11 Pages 2007
Effects of Stabilizers on the Destabilization of Proteins upon Adsorption to Aluminum Salt Adjuvants Fulltext Access 11 Pages 2007
Nanoparticulate Systems for Nasal Delivery of Drugs: A Real Improvement over Simple Systems? Fulltext Access 11 Pages 2007
Lyophilization Cycle Development for a High-Concentration Monoclonal Antibody Formulation Lacking a Crystalline Bulking Agent Fulltext Access 11 Pages 2007
Effect of Characteristics of Compounds on Maintenance of an Amorphous State in Solid Dispersion with Crospovidone Fulltext Access 11 Pages 2007
Variability in Human Skin Permeability In Vitro: Comparing Penetrants with Different Physicochemical Properties Fulltext Access 11 Pages 2007
Investigation of the Effects of Pharmaceutical Processing Upon Solid-State NMR Relaxation Times and Implications to Solid-State Formulation Stability Fulltext Access 11 Pages 2007
Processing-Induced Phase Transitions of Theophylline—Implications on the Dissolution of Theophylline Tablets Fulltext Access 11 Pages 2007
The Influence of Mechanical Processing of Dry Powder Inhaler Carriers on Drug Aerosolization Performance Fulltext Access 11 Pages 2007
Solving Molecular Crystal Structures from X-ray Powder Diffraction Data: The Challenges Posed by γ-Carbamazepine and Chlorothiazide N,N,-Dimethylformamide (1/2) Solvate Fulltext Access 11 Pages 2007
Investigations on Solid-Solid Phase Transformation of 5-Methyl-2-[(4-Methyl-2-Nitrophenyl)Amino]-3- Thiophenecarbonitrile Fulltext Access 11 Pages 2007
Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2âmethoxyestradiol Fulltext Access 11 Pages 2007
Assessing the antifungal activity, pharmacokinetics, and tissue distribution of amphotericin B following the administration of Abelcet® and AmBisome® in combination with caspofungin to rats infected with Aspergillus fumigatus Fulltext Access 11 Pages 2007
The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody Fulltext Access 11 Pages 2007
Polymerâsurfactant nanoparticles for sustained release of waterâsoluble drugs Fulltext Access 11 Pages 2007
Evaluation of an in vitro in vivo correlation for nebulizer delivery using artificial neural networks Fulltext Access 11 Pages 2007
Sucrose acetate isobutyrate as an In Situ forming system for sustained risperidone release Fulltext Access 11 Pages 2007
Tablets With Material Gradients Fabricated by Three-Dimensional Printing Fulltext Access 11 Pages 2007
Controlled porosityâosmotic pump pellets of a poorly waterâsoluble drug using sulfobutyletherâβâcyclodextrin, (SBE)7MâβâCD, as a solubilizing and osmotic agent Fulltext Access 11 Pages 2007
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux Fulltext Access 11 Pages 2007
Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial Fulltext Access 11 Pages 2007
Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil Fulltext Access 11 Pages 2007
Interferon-γ induced disruption of GABAergic inhibition in the spinal dorsal horn in vivo Fulltext Access 11 Pages 2007
A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile Fulltext Access 11 Pages 2007
Cyclothiazide selectively inhibits mGluR1 receptors interacting with a common allosteric site for non-competitive antagonists Fulltext Access 11 Pages 2007
Pharmacological and computational analysis of alpha-subunit preferential GABAA positive allosteric modulators on the rat septo-hippocampal activity Fulltext Access 11 Pages 2007
Concatemers of brain Kv1 channel α subunits that give similar K+ currents yield pharmacologically distinguishable heteromers Fulltext Access 11 Pages 2007
Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat Fulltext Access 11 Pages 2007
Neuroprotective effect of taurine against focal cerebral ischemia in rats possibly mediated by activation of both GABAA and glycine receptors Fulltext Access 11 Pages 2007
Partial agonist and neuromodulatory activity of S 24795 for alpha7 nAChR responses of hippocampal interneurons Fulltext Access 11 Pages 2007
Differential regulation of glutamate receptor-mediated BDNF mRNA expression in the cerebellum and its defects in stargazer mice Fulltext Access 11 Pages 2007
Pre- and postsynaptic effects of kainate on layer II/III pyramidal cells in rat neocortex Fulltext Access 11 Pages 2007
Design of PCRâamplified DNA fragments for in vivo gene delivery: Sizeâdependency on stability and transgene expression Fulltext Access 11 Pages 2007
Chronic olanzapine activates the Stat3 signal transduction pathway and alters expression of components of the 5-HT2A receptor signaling system in rat frontal cortex Fulltext Access 11 Pages 2007
Inhibition of voltage-gated channel currents in rat auditory cortex neurons by salicylate Fulltext Access 11 Pages 2007
Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: A novel approach for controlling status epilepticus Fulltext Access 11 Pages 2007
Blockade of alcohol's amnestic activity in humans by an α5 subtype benzodiazepine receptor inverse agonist Fulltext Access 11 Pages 2007
Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus Fulltext Access 11 Pages 2007
Presynaptic mechanisms involved in the expression of STP and LTP at CA1 synapses in the hippocampus Fulltext Access 11 Pages 2007
Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets Fulltext Access 11 Pages 2007
Effects of Kaempferia Parviflora Extracts and Their Flavone Constituents on P-glycoprotein Function Fulltext Access 11 Pages 2007
Hydrocolloid Carriers with Filler Inclusionfor Diltiazem Hydrochloride Release Fulltext Access 11 Pages 2007
Elastic Liposomes Mediated Transdermal Deliveryof an Anti-Hypertensive Agent: Propranolol Hydrochloride Fulltext Access 11 Pages 2007
Mental disorders among persons with chronic back or neck pain: Results from the world mental health surveys Fulltext Access 11 Pages 2007
Are laser-evoked brain potentials modulated by attending to first or second pain? Fulltext Access 11 Pages 2007
ASIC3 in muscle mediates mechanical, but not heat, hyperalgesia associated with muscle inflammation Fulltext Access 11 Pages 2007
Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways Fulltext Access 11 Pages 2007
Lamotrigine for treatment of pain associated with diabetic neuropathy: Results of two randomized, double-blind, placebo-controlled studies Fulltext Access 11 Pages 2007
Somatotopic organization of the processing of muscle and cutaneous pain in the left and right insula cortex: A single-trial fMRI study Fulltext Access 11 Pages 2007
Spatial summation of mechanically evoked muscle pain and painful aftersensations in normal subjects and fibromyalgia patients Fulltext Access 11 Pages 2007
Mast cell degranulation activates a pain pathway underlying migraine headache Fulltext Access 11 Pages 2007
Nociceptive nerve activity in an experimental model of knee joint osteoarthritis of the guinea pig: Effect of intra-articular hyaluronan application Fulltext Access 11 Pages 2007
Effects of vasectomy surgery and meloxicam treatment on faecal corticosterone levels and behaviour in two strains of laboratory mouse Fulltext Access 11 Pages 2007
Bradykinin-induced nociceptor sensitisation to heat depends on cox-1 and cox-2 in isolated rat skin Fulltext Access 11 Pages 2007
The characteristics of chronic central pain after traumatic brain injury Fulltext Access 11 Pages 2007
Psychosocial factors associated with pain intensity, pain-related interference, and psychological functioning in persons with multiple sclerosis and pain Fulltext Access 11 Pages 2007
The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: Evidence for ethnic differences Fulltext Access 11 Pages 2007
Altered spinal arachidonic acid turnover after peripheral nerve injury regulates regional glutamate concentration and neuropathic pain behaviors in rats Fulltext Access 11 Pages 2007
Peripheral and central components of habituation of heat pain perception and evoked potentials in humans Fulltext Access 11 Pages 2007
Differential expression patterns of cytokines in complex regional pain syndrome Fulltext Access 11 Pages 2007
Health care practitioners’ attitudes and beliefs about low back pain: A systematic search and critical review of available measurement tools Fulltext Access 11 Pages 2007
Modulation of persistent nociceptive inputs in the anterior pretectal nucleus of the rat Fulltext Access 11 Pages 2007
Subsequent exposure to the choline uptake enhancer MKC-231 antagonizes phencyclidine-induced behavioral deficits and reduction in septal cholinergic neurons in rats Fulltext Access 11 Pages 2007
Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice Fulltext Access 11 Pages 2007
Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y1 receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression Fulltext Access 11 Pages 2007
How do glial–neuronal interactions fit into current neurotransmitter hypotheses of schizophrenia? Fulltext Access 11 Pages 2007
Determination of the Hydrolysis Kinetics of α-Naphthyl Acetate in Micellar Systems and the Effect of HPMC (catalyst present) Fulltext Access 11 Pages 2007
Biodistribution and Pharmacokinetic Analysis of Long-Circulating Thiolated Gelatin Nanoparticles Following Systemic Administration in Breast Cancer-Bearing Mice Fulltext Access 11 Pages 2007
Analysis of Coating Structures and Interfaces in Solid Oral Dosage Forms by Three Dimensional Terahertz Pulsed Imaging Fulltext Access 11 Pages 2007
Factors Affecting the Formation of Eutectic Solid Dispersions and Their Dissolution Behavior Fulltext Access 11 Pages 2007
A Mechanistic and Kinetic Study of the β-Lactone Hydrolysis of Salinosporamide A (NPI-0052), A Novel Proteasome Inhibitor Fulltext Access 11 Pages 2007
High Pressure Differential Scanning Calorimetry Investigations on the Pressure Dependence of the Melting of Paracetamol Polymorphs I and II Fulltext Access 11 Pages 2007
Investigation of the Influence of Particle Size on the Excipient Percolation Thresholds of HPMC Hydrophilic Matrix Tablets Fulltext Access 11 Pages 2007
Application of Direct Crystallization for Racemic Compound Propranolol Hydrochloride Fulltext Access 11 Pages 2007
Emergence of a spermine-sensitive, non-inactivating conductance in mature hippocampal CA1 pyramidal neurons upon reduction of extracellular Ca2+: Dependence on intracellular Mg2+ and ATP Fulltext Access 11 Pages 2007
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant Fulltext Access 11 Pages 2007
Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function Fulltext Access 11 Pages 2007
NGF-dependent formation of ruffles in PC12D cells required a different pathway from that for neurite outgrowth Fulltext Access 11 Pages 2007
Control of tangential/non-radial migration of neurons in the developing cerebral cortex Fulltext Access 11 Pages 2007
Molecular and cellular function of ALS2/alsin: Implication of membrane dynamics in neuronal development and degeneration Fulltext Access 11 Pages 2007
Late appearance of glutamate transporter defects in a murine model of ALS–parkinsonism dementia complex Fulltext Access 11 Pages 2007
Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability Fulltext Access 11 Pages 2007
Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes Fulltext Access 11 Pages 2007
Mediators, moderators, and predictors of therapeutic change in cognitive–behavioral therapy for chronic pain Fulltext Access 11 Pages 2007
Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: Increased expression of ATF-3 and pharmacological characterisation Fulltext Access 11 Pages 2007
Systematic review of observational (behavioral) measures of pain for children and adolescents aged 3 to 18 years Fulltext Access 11 Pages 2007
Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice Fulltext Access 11 Pages 2007
Preferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel Fulltext Access 11 Pages 2007