High throughput protein crystallography: Developments in crystallisation, data collection and data processing Fulltext Access 6 Pages 2006
Allosteric modulation of monoamine transporters – new drug targets in depression Fulltext Access 6 Pages 2006
New technologies for assessing UDP-glucuronosyltransferase (UGT) metabolism in drug discovery and development Fulltext Access 6 Pages 2006
Targeting the p40 cytokines interleukin (IL)-12 and IL-23 in Crohn's disease Fulltext Access 6 Pages 2006
Use of high-throughput LC–MS/MS proteomics technologies in drug discovery Fulltext Access 6 Pages 2006
Telomeres and telomerase in aging and cancer: Lessons learned from experimental model systems Fulltext Access 6 Pages 2006
Defining and maintaining a high quality screening collection: the GSK experience Fulltext Access 6 Pages 2006
Recombinant polyclonal antibodies: the next generation of antibody therapeutics? Fulltext Access 6 Pages 2006
A Convenient Method for Estimating the Quantity of Drug Eliminated by the Routes Other than Hepatic Metabolism and Renal Excretion and the Fraction of Drug that Reaches the “First Pass” after Oral Administration Fulltext Access 6 Pages 2006
Predicting the aerosol performance of dry powder inhalation formulations by interparticulate interaction analysis using inverse gas chromatography Fulltext Access 6 Pages 2006
Application of an exact mathematical model and the steady-state approximation to the kinetics of the reaction of cysteine and hydrogen peroxide in aqueous solution: A reply to the Ashby and Nagy commentary Fulltext Access 6 Pages 2006
Effect of sustained limb ischemia on norepinephrine release from skeletal muscle sympathetic nerve endings Fulltext Access 6 Pages 2006
Therapeutic window of bradykinin B2 receptor inhibition after focal cerebral ischemia in rats Fulltext Access 6 Pages 2006
The role of Toll: How therapies targeting Toll-like receptors treat skin diseases Fulltext Access 6 Pages 2006
Adoptive T lymphocyte therapy to fight cytomegalovirus infection in immunodeficient hosts Fulltext Access 6 Pages 2006
Allogeneic hematopoietic stem cell transplantation for malignant disease: How to prevent graft-versus-host disease without jeopardizing the graft-versus-tumor effect? Fulltext Access 6 Pages 2006
Extending the life of β-lactam antibiotics: New β-lactamase inhibitors Fulltext Access 6 Pages 2006
Heme detoxification and antimalarial drugs – Known mechanisms and future prospects Fulltext Access 6 Pages 2006
Effects of dextromethorphan on rats' acquisition of responding with delayed reinforcement Fulltext Access 6 Pages 2006
The effects of long-term chronic buprenorphine treatment on the locomotor and nucleus accumbens dopamine response to acute heroin and cocaine in rats Fulltext Access 6 Pages 2006
Lack of behavioral and neuropathological effects of dietary β-methylamino-l-alanine (BMAA) in mice Fulltext Access 6 Pages 2006
Behavioral and genoprotective effects of Vaccinium berries intake in mice Fulltext Access 6 Pages 2006
Beta-adrenergic-mediated inhibition of feeding by mercaptoacetate in food-deprived rats Fulltext Access 6 Pages 2006
Differential progesterone effects on defensive burying and forced swimming tests depending upon a gradual decrease or an abrupt suppression schedules Fulltext Access 6 Pages 2006
Depression and serum adiponectin and adipose omega-3 and omega-6 fatty acids in adolescents Fulltext Access 6 Pages 2006
Corticotropin-releasing factor receptor type 1, but not type 2, in the ventromedial hypothalamus modulates dopamine release in female rats Fulltext Access 6 Pages 2006
Involvement of hypothalamic pituitary adrenal axis on the nifedipine-induced antinociception and tolerance in rats Fulltext Access 6 Pages 2006
Inhibition of the cyclooxygenase pathway attenuates morphine-induced conditioned place preference in mice Fulltext Access 6 Pages 2006
Increased nicotine self-administration following prenatal exposure in female rats Fulltext Access 6 Pages 2006
Conditioned place preference induced by morphine and morphine-6-glucuronide in mice Fulltext Access 6 Pages 2006
The effects of two non-pharmacologic pain management methods for intramuscular injection pain in children Fulltext Access 6 Pages 2006
High correlation but inadequate point-to-point agreement, between conventional mechanical and electronical visual analogue scale for assessment of acute postoperative pain after general surgery Fulltext Access 6 Pages 2006
Major depressive disorders: clinical efficacy and tolerability of agomelatine, a new melatonergic agonist Fulltext Access 6 Pages 2006
Escitalopram versus paroxetine for social anxiety disorder: An analysis of efficacy for different symptom dimensions Fulltext Access 6 Pages 2006
The serotonin-1Dβ receptor gene and severity of obsessive-compulsive disorder in women with bulimia nervosa Fulltext Access 6 Pages 2006
Genetic polymorphisms of alcohol and aldehyde dehydrogenase, dopamine and serotonin transporters in familial and non-familial alcoholism Fulltext Access 6 Pages 2006
Effect of vitamin E on memory retention in rats: Possible involvement of cholinergic system Fulltext Access 6 Pages 2006
Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders Fulltext Access 6 Pages 2006
Drug-induced home cage conspecifics' behavior can potentiate behavioral sensitization in mice Fulltext Access 6 Pages 2006
Biological assay challenges from compound solubility: strategies for bioassay optimization Fulltext Access 6 Pages 2006
New perspectives on the impact of cytochrome P450 3A expression for pediatric pharmacology Fulltext Access 6 Pages 2006
Cell-surface and cytokine biomarkers in autoimmune and inflammatory diseases Fulltext Access 6 Pages 2006
Flight reactions induced by injection of glutamate N-methyl-d-aspartate receptor agonist into the rat dorsolateral periaqueductal gray are not dependent on endogenous nitric oxide Fulltext Access 6 Pages 2006
Monoamine levels in the nucleus accumbens correlate with male sexual behavior in middle-aged rats Fulltext Access 6 Pages 2006
Neuroprotective effects of olanzapine in a rat model of neurodevelopmental injury Fulltext Access 6 Pages 2006
Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior Fulltext Access 6 Pages 2006
Neuroendocrine and reproductive aspects of adult male rats exposed neonatally to an antiestrogen Fulltext Access 6 Pages 2006
Modulation of a (+)amphetamine discriminative stimulus in rats by 8-hydroxy-2-(N,N-di-n-propylamino)tetralin (8-OH DPAT) Fulltext Access 6 Pages 2006
The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine Fulltext Access 6 Pages 2006
Anticonvulsant effect of the calcineurin inhibitor ascomycin on seizures induced by picrotoxin microperfusion in the rat hippocampus Fulltext Access 6 Pages 2006
Cholinergic overstimulation supports conditioned-facilitated startle but not conditioned hyperalgesia Fulltext Access 6 Pages 2006
Alcohol consumption is preferred to water in rats pretreated with intravenous cocaine Fulltext Access 6 Pages 2006
Antinociceptive tolerance revealed by cumulative intracranial microinjections of morphine into the periaqueductal gray in the rat Fulltext Access 6 Pages 2006
Anticipation and consumption of food each increase the concentration of neuroactive steroids in rat brain and plasma Fulltext Access 6 Pages 2006
The effects of serotonin reuptake inhibitors on locomotor activity in gerbils Fulltext Access 6 Pages 2006
Dehydroepiandrosterone sulfate, cortisol, mood state and smoking cessation: Relationship to relapse status at 4-week follow-up Fulltext Access 6 Pages 2006