Measures of the aversive effects of drugs: A comparison of conditioned taste and place aversions Fulltext Access 7 Pages 2015
Effects of chronic sodium alendronate on depression and anxiety in a menopausal experimental model Fulltext Access 7 Pages 2015
Proficient motor impulse control in Parkinson disease patients with impulsive and compulsive behaviors Fulltext Access 7 Pages 2015
Early-life risperidone administration alters maternal-offspring interactions and juvenile play fighting Fulltext Access 7 Pages 2015
Erythropoietin improves synaptic plasticity and memory deficits by decrease of the neurotransmitter release probability in the rat model of Alzheimer's disease Fulltext Access 7 Pages 2015
The antinociceptive effect of stimulating the retrosplenial cortex in the rat tail-flick test but not in the formalin test involves the rostral anterior cingulate cortex Fulltext Access 7 Pages 2015
Nicotine withdrawal in selectively bred high and low nicotine preferring rat lines Fulltext Access 7 Pages 2015
Glutamatergic transmission is involved in the long lasting sexual inhibition of sexually exhausted male rats Fulltext Access 7 Pages 2015
Age moderates the effect of acute dopamine depletion on passive avoidance learning Fulltext Access 7 Pages 2015
Investigation of the role of non-selective calcium channel blocker (flunarizine) on cerebral ischemic-reperfusion associated cognitive dysfunction in aged mice Fulltext Access 7 Pages 2015
The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats Fulltext Access 7 Pages 2015
Combined varenicline and naltrexone treatment reduces smoking topography intensity in heavy-drinking smokers Fulltext Access 7 Pages 2015
Pharmacological validation of the free-exploratory paradigm in male Wistar rats: A proposed test of trait anxiety Fulltext Access 7 Pages 2015
Validation and scopolamine-reversal of latent learning in the water maze utilizing a revised direct platform placement procedure Fulltext Access 7 Pages 2015
Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion Fulltext Access 7 Pages 2015
Central and peripheral antinociceptive activity of 3-(2-oxopropyl)-3-hydroxy-2-oxindoles Fulltext Access 7 Pages 2015
Functional reconstitution of glycinergic synapses incorporating defined glycine receptor subunit combinations Fulltext Access 7 Pages 2015
Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington's disease Fulltext Access 7 Pages 2015
Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress Fulltext Access 7 Pages 2015
The benzodiazepine midazolam acts on the expression of the defensive behavior, but not on the processing of aversive information, produced by exposure to the elevated plus maze and electrical stimulations applied to the inferior colliculus of rats Fulltext Access 7 Pages 2015
The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus Fulltext Access 7 Pages 2015
Modular chemical probes for visualizing and tracking endogenous ion channels Fulltext Access 7 Pages 2015
Crystal Structure and Desolvation Behaviour of the Tadalafil Monosolvates with Acetone and Methyl Ethyl Ketone Fulltext Access 7 Pages 2015
Treat the brain and treat the periphery: toward a holistic approach to major depressive disorder Fulltext Access 7 Pages 2015
Designing novel building blocks is an overlooked strategy to improve compound quality Fulltext Access 7 Pages 2015
Drug discovery FAQs: workflows for answering multidomain drug discovery questions Fulltext Access 7 Pages 2015
Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide Fulltext Access 7 Pages 2015
How the flexibility of human histone deacetylases influences ligand binding: an overview Fulltext Access 7 Pages 2015
Extending kinome coverage by analysis of kinase inhibitor broad profiling data Fulltext Access 7 Pages 2015
Discovery of selective phosphatidylinositol 3-kinase inhibitors to treat hematological malignancies Fulltext Access 7 Pages 2015
Impact of recent innovations in the use of mass cytometry in support of drug development Fulltext Access 7 Pages 2015
Lost in space: design of experiments and scientific exploration in a Hogarth Universe Fulltext Access 7 Pages 2015
Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective Fulltext Access 7 Pages 2015
Development of Flow Imaging Analysis for Subvisible Particle Characterization in Glatiramer Acetate Fulltext Access 7 Pages 2015
Osmotic Virial Coefficients as Access to the Protein Partitioning in Aqueous Two-Phase Systems Fulltext Access 7 Pages 2015
Measurement of the Average Mass of Proteins Adsorbed to a Nanoparticle by Using a Suspended Microchannel Resonator Fulltext Access 7 Pages 2015
Technical Decision Making with Higher Order Structure Data: Utilization of Differential Scanning Calorimetry to Elucidate Critical Protein Structural Changes Resulting from Oxidation Fulltext Access 7 Pages 2015
Engineering of Recombinant Spider Silk Proteins Allows Defined Uptake and Release of Substances Fulltext Access 7 Pages 2015
Using Improved Serial Blood Sampling Method of Mice to Study Pharmacokinetics and Drug-Drug Interaction Fulltext Access 7 Pages 2015
Effect of the Subcutaneous Environment on Phase-Sensitive In Situ-Forming Implant Drug Release, Degradation, and Microstructure Fulltext Access 7 Pages 2015
Estimation of Crystallinity of Nifedipine-Polyvinylpyrrolidone Solid Dispersion by Usage of Terahertz Time-Domain Spectroscopy and of X-Ray Powder Diffractometer Fulltext Access 7 Pages 2015
Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator Fulltext Access 7 Pages 2015
Comprehensive assessment of vascular health in patients; towards endothelium-guided therapy Fulltext Access 7 Pages 2015
Agmatine attenuates lipopolysaccharide induced anorexia and sickness behavior in rats Fulltext Access 7 Pages 2015
Cocaine decreases saccharin preference without altering sweet taste sensitivity Fulltext Access 7 Pages 2015
An initial investigation of associations between dopamine-linked genetic variation and smoking motives in African Americans Fulltext Access 7 Pages 2015
Ability of natural astaxanthin from shrimp by-products to attenuate liver oxidative stress in diabetic rats Fulltext Access 7 Pages 2015
Gambogic amide selectively upregulates TrkA expression and triggers its activation Fulltext Access 7 Pages 2015
Effects of microinjection of histamine into the anterior cingulate cortex on pain-related behaviors induced by formalin in rats Fulltext Access 7 Pages 2015
Hypocholesterolemic and choleretic effects of three dimethoxycinnamic acids in relation to 2,4,5-trimethoxycinnamic acid in rats fed with a high-cholesterol/cholate diet Fulltext Access 7 Pages 2015
Subacute poisoning of mice with deltamethrin produces memory impairment, reduced locomotor activity, liver damage and changes in blood morphology in the mechanism of oxidative stress Fulltext Access 7 Pages 2015
Pharmacokinetics of cotinine in rats: A potential therapeutic agent for disorders of cognitive function Fulltext Access 7 Pages 2015
Antidepressant-like effect of modafinil in mice: Evidence for the involvement of the dopaminergic neurotransmission Fulltext Access 7 Pages 2015
Towards a comprehensive endothelial biomarkers profiling and endothelium-guided pharmacotherapy Fulltext Access 7 Pages 2015
Mechanisms of morphine–venlafaxine interactions in diabetic neuropathic pain model Fulltext Access 7 Pages 2015
Taking aim at a dynamic target: Noscapinoids as microtubule-targeted cancer therapeutics Fulltext Access 7 Pages 2015
Acetylsalicylic acid resistance risk factors in patients with myocardial infarction Fulltext Access 7 Pages 2015
Influence of tobacco smoke exposure on pharmacokinetics of ethyl alcohol in alcohol preferring and non-preferring rats Fulltext Access 7 Pages 2015
Pretreatment with magnesium ameliorates lipopolysaccharide-induced liver injury in mice Fulltext Access 7 Pages 2015
Effects of simvastatin on malondialdehyde level and esterase activity in plasma and tissue of normolipidemic rats Fulltext Access 7 Pages 2015
Effects of neuroleptics administration on adult neurogenesis in the rat hypothalamus Fulltext Access 7 Pages 2015
Protective effect of gallic acid against bleomycin-induced pulmonary fibrosis in rats Fulltext Access 7 Pages 2015
The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics Fulltext Access 7 Pages 2015
Cost-Constrained Optimal Sampling for System Identification in Pharmacokinetics Applications with Population Priors and Nuisance Parameters Fulltext Access 7 Pages 2015
Solubility and Crystal Nucleation in Organic Solvents of Two Polymorphs of Curcumin Fulltext Access 7 Pages 2015
Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their Consequent Solubility–Permeability Interplay Fulltext Access 7 Pages 2015
Evaluation of Acid Tolerance of Drugs Using Rats and Dogs Controlled for Gastric Acid Secretion Fulltext Access 7 Pages 2015
Synthesis of some new 5-substituted-2-((6-chloro-3,4-methylenedioxyphenyl)methylthio)-1,3,4-oxadiazole derivatives as suitable antibacterial inhibitors Fulltext Access 7 Pages 2015
Alleviation of haloperidol induced oxidative stress in rats: Effects of sucrose vs grape seed extract Fulltext Access 7 Pages 2015
Design, synthesis and evaluation of genistein-polyamine conjugates as multi-functional anti-Alzheimer agents Fulltext Access 7 Pages 2015
Effects of fluoxetine on protein expression of potassium ion channels in the brain of chronic mild stress rats Fulltext Access 7 Pages 2015
Synthesis, potential anticonvulsant and antidepressant effects of 2-(5-methyl-2,3-dioxoindolin-1-yl)acetamide derivatives Fulltext Access 7 Pages 2015
Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism Fulltext Access 7 Pages 2015
Clozapine use in childhood and adolescent schizophrenia: A nationwide population-based study Fulltext Access 7 Pages 2015
Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis Fulltext Access 7 Pages 2015
Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders Fulltext Access 7 Pages 2015
Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity Fulltext Access 7 Pages 2015
Transcription and protein synthesis inhibitors influence long-term effects of acetyl-l-carnitine on non-associative learning in the leech Fulltext Access 7 Pages 2015
Endothelial dysfunction impairs vascular neurotransmission in tail arteries Fulltext Access 7 Pages 2015
Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury Fulltext Access 7 Pages 2015
Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction Fulltext Access 7 Pages 2015
Challenges in profiling and lead optimization of drug discovery for methyltransferases Fulltext Access 7 Pages 2015
Computational modeling helps uncover mechanisms related to the progression of emphysema Fulltext Access 7 Pages 2015