Drug localization and targeting with receptor microscopic autoradiography Fulltext Access 16 Pages 2005
Modulation of neurotransmitter release by the second messenger-activated protein kinases: Implications for presynaptic plasticity Fulltext Access 16 Pages 2005
Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners Fulltext Access 16 Pages 2005
Poly(ADP-ribose) polymerase-mediated cell injury in acute renal failure Fulltext Access 16 Pages 2005
Vitamin D-induced up-regulation of tumour necrosis factor alpha (TNF-α) in prostate cancer cells Fulltext Access 16 Pages 2005
T cells recognize PD(N/T)R motif common in a variable number of tandem repeat and degenerate repeat sequences of MUC1 Fulltext Access 16 Pages 2005
Detection of a novel population of fetal thymocytes characterized by preferential emigration and a TCRγδ+ T cell fate after dioxin exposure Fulltext Access 16 Pages 2005
A T-cell-dependent humoral immune response is preserved during the administration of the nerve agent pre-treatment pyridostigmine bromide in a murine model Fulltext Access 16 Pages 2005
Ethnobotanical and ethnomedicinal uses of plants in the district of Acquapendente (Latium, Central Italy) Fulltext Access 16 Pages 2005
The protein kinase C inhibitor, bisindolylmaleimide (I), inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells Fulltext Access 16 Pages 2005
Preincubation with sodium ascorbate potentiates insulin-dependent PKB/Akt and c-Jun phosphorylation in L6 rat myoblasts challenged with reactive oxygen/nitrogen species Fulltext Access 16 Pages 2005
Choice of cardiac tissue plays an important role in the evaluation of drug-induced prolongation of the QT interval in vitro in rabbit Fulltext Access 16 Pages 2005
Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure Fulltext Access 16 Pages 2005
Bone resorption by aryl hydrocarbon receptor-expressing osteoclasts is not disturbed by TCDD in short-term cultures Fulltext Access 16 Pages 2005
A Korean herbal medicine, Panax notoginseng, prevents liver fibrosis and hepatic microvascular dysfunction in rats Fulltext Access 16 Pages 2005
Relaxant effects of pravastatin, atorvastatin and cerivastatin on isolated rat aortic rings Fulltext Access 16 Pages 2005
Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines Fulltext Access 16 Pages 2005
Different pharmacological profile of two closely related endocannabinoid ester analogs Fulltext Access 16 Pages 2005
Role of lipids and lipid signaling in the development of cannabinoid tolerance Fulltext Access 16 Pages 2005
Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels Fulltext Access 16 Pages 2005
Angiotensin peptides modulatory system: how is it implicated in the control of seizure susceptibility? Fulltext Access 16 Pages 2005
Orally administrated rare earth element cerium induces metallothionein synthesis and increases glutathione in the mouse liver Fulltext Access 16 Pages 2005
Neuroadaptations to hyperdopaminergia in dopamine D3 receptor-deficient mice Fulltext Access 16 Pages 2005
β-Adrenergic activation reveals impaired cardiac calcium handling at early stage of diabetes Fulltext Access 16 Pages 2005
Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay- directed fractionation techniques Fulltext Access 16 Pages 2005
A single exposure to novelty differentially affects the accumbal dopaminergic system of apomorphine-susceptible and apomorphine-unsusceptible rats Fulltext Access 16 Pages 2005
Access to exercise and its relation to cardiovascular health and gene expression in laboratory animals Fulltext Access 16 Pages 2005
Clinical impact of vasomotor function assessment and the role of ACE-inhibitors and statins Fulltext Access 16 Pages 2005
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis Fulltext Access 16 Pages 2005
Monochloramine induces acute and protracted colitis in the rat: Response to pharmacological treatment Fulltext Access 16 Pages 2005
Disorders in bone metabolism of female rats chronically exposed to cadmium Fulltext Access 16 Pages 2005
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFκB activation and cyclin D1 up-regulation Fulltext Access 16 Pages 2005
Comprehensive analysis of differential gene expression profiles on carbon tetrachloride-induced rat liver injury and regeneration Fulltext Access 16 Pages 2005
Saeng-Ji-Hwang has a protective effect on adriamycin-induced cytotoxicity in cardiac muscle cells Fulltext Access 16 Pages 2005
L-carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: Different participation of NO and COX-products Fulltext Access 16 Pages 2005
Inhibitory effect of 6-hydroxy-7-methoxychroman-2-carboxylic acid phenylamide on nitric oxide and interleukin-6 production in macrophages Fulltext Access 16 Pages 2005
Enhancing the uptake of dextromethorphan in the CNS of rats by concomitant administration of the P-gp inhibitor verapamil Fulltext Access 16 Pages 2005
Initial conditions of psychotropic drug response: Studies of serotonin transporter long promoter region (5-HTTLPR), serotonin transporter efficiency, cytokine and kinase gene expression relevant to depression and antidepressant outcome Fulltext Access 16 Pages 2005
Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1-dependent p-nitrophenol hydroxylation in the liver microsomes of streptozotocin-induced type 1 diabetic rats Fulltext Access 16 Pages 2005
Intracerebroventricular d-Pen2, d-Pen5-enkephalin administration soon after stressor imposition influences behavioral responsivity to a subsequent stressor encounter in CD-1 mice Fulltext Access 17 Pages 2005
Dielectric Studies of Molecular Motions in Amorphous Solid and Ultraviscous Acetaminophen Fulltext Access 17 Pages 2005
The effects of dopaminergic/serotonergic reuptake inhibition on maternal behavior, maternal aggression, and oxytocin in the rat Fulltext Access 17 Pages 2005
Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach? Fulltext Access 17 Pages 2005
Comparative metabonomics of differential hydrazine toxicity in the rat and mouse Fulltext Access 17 Pages 2005
Selective rat lung endothelial targeting with a new set of monoclonal antibodies to angiotensin I-converting enzyme Fulltext Access 17 Pages 2005
Cell cycle specific induction of apoptosis and necrosis by paclitaxel in the leukemic U937 cells Fulltext Access 17 Pages 2005
Interface of physical and emotional stress regulation through the endogenous opioid system and μ-opioid receptors Fulltext Access 17 Pages 2005
Dementia of Alzheimer's disease and other neurodegenerative disorders-memantine, a new hope Fulltext Access 17 Pages 2005
Cardiac transcription factor Csx/Nkx2-5: Its role in cardiac development and diseases Fulltext Access 17 Pages 2005
Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias Fulltext Access 17 Pages 2005
The dopamine D3 receptor and drug dependence: Effects on reward or beyond? Fulltext Access 17 Pages 2005
An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery Fulltext Access 17 Pages 2005
Pharmacological basis for the use of turmeric in gastrointestinal and respiratory disorders Fulltext Access 17 Pages 2005
Regulation of aminopeptidase N (EC 3.4.11.2; APN; CD13) by interferon-γ on the HL-60 cell line Fulltext Access 17 Pages 2005
Insulin stimulates Ca2+ uptake via PKC, cAMP, and p38 MAPK in mouse embryonic stem cells Fulltext Access 17 Pages 2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure Fulltext Access 17 Pages 2005
An approach to solvent screening for crystallization of polymorphic pharmaceuticals and fine chemicals Fulltext Access 17 Pages 2005
Role of the α subunit in the modulation of GABAA receptors by anabolic androgenic steroids Fulltext Access 17 Pages 2005
RGS-Rz and RGS9-2 proteins control mu-opioid receptor desensitisation in CNS: the role of activated Gαz subunits Fulltext Access 17 Pages 2005
Methodological challenges surrounding direct-to-consumer advertising research-The measurement conundrum Fulltext Access 17 Pages 2005
Treatment perceptions and attitudes of older human immunodeficiency virus-infected adults Fulltext Access 17 Pages 2005
The Authority/Pharmacotherapy Care model: an explanatory model of the drug use process in primary careâ Fulltext Access 17 Pages 2005
Histamine H1 receptor antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/IκB/NF-κB signal cascades Fulltext Access 17 Pages 2005
Chemomodulatory effect of Ficus racemosa extract against chemically induced renal carcinogenesis and oxidative damage response in Wistar rats Fulltext Access 17 Pages 2005
The inhibitory effect of a Korean herbal medicine, Zedoariae rhizoma, on growth of cultured human hepatic myofibroblast cells Fulltext Access 17 Pages 2005
Non-drug-related electrocardiographic features in animal models in safety pharmacology Fulltext Access 17 Pages 2005
Differential effect of sodium arsenite during the activation of human CD4+ and CD8+ T lymphocytes Fulltext Access 17 Pages 2005
Macrophage immunomodulatory activity of polysaccharides isolated from Juniperus scopolorum Fulltext Access 17 Pages 2005
Safety profile of a nicotine lozenge compared with thatof nicotine gum in adult smokers with underlying medical conditions: A 12-week, randomized, open-label study Fulltext Access 17 Pages 2005
Treatment of symptomatic diabetic peripheral neuropathy with the protein kinase C β-inhibitor ruboxistaurin mesylate during a 1-year, randomized, placebo-controlled, double-blind clinical trial Fulltext Access 17 Pages 2005
Development and validity testing of the neuropathy total symptom score-6: Questionnaire for the study of sensory symptoms of diabetic peripheral neuropathy Fulltext Access 17 Pages 2005
A preclinical comparison between different opioids: antinociceptive versus adverse effects Fulltext Access 18 Pages 2005
Recovery from experimental Parkinson's disease in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride treated marmoset with the melatonin analogue ML-23 Fulltext Access 18 Pages 2005
Chinese medicinal materials and their interface with Western medical concepts Fulltext Access 18 Pages 2005
Patient controlled intravenous opioid analgesia versus conventional opioid analgesia for postoperative pain control: A quantitative systematic review Fulltext Access 18 Pages 2005
Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases Fulltext Access 18 Pages 2005
Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix? Fulltext Access 18 Pages 2005
Neuroprotectant effects of iso-osmolar d-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers Fulltext Access 18 Pages 2005
Calorimetric Investigation of the Structural Relaxation of Amorphous Materials: Evaluating Validity of the Methodologies Fulltext Access 18 Pages 2005