Mitochondrial metabolism in aging: Effect of dietary interventions

► Mitochondrial energy metabolism is central toward aging. ► We focus on the relationship between mitochondrial redox state, aging and dietary interventions. ► Which modifications induced by diet are central in aging remains to be fully understood. ► Diets used for laboratory animals are variable, and of difficult comparison with humans. ► Mechanistically understanding effects of diets will help translate into positive human effects.