Reactive oxygen species-dependent wound responses in animals and plants

► Reactive oxygen species coordinate the wound response in plants and animals. ► NADPH oxidases are required to generate reactive oxygen signals during wounding. ► A gradient of H2O2 extends from the wound site in animals and attracts neutrophils. ► A systemic autopropagating wave of H2O2 extends from wound sites in plants. ► The reactive oxygen wave in plants triggers defense pathways in remote tissues.