A 1H NMR metabolic profiling to the assessment of protein tyrosine phosphatase 1B role in liver regeneration after partial hepatectomy

► PTP1B KO mice showed an earlier and more sustained liver regeneration. ► PTP1B has a pivotal role in liver regeneration that affects the metabolic level. ► 1H NMR can differentiate metabolic response of PTP1B KO liver regeneration vs WT.