Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy

► MCPIP mediates angiogenesis by inflammatory agents, TNF-α, IL-1β, IL-8 and MCP-1. ► MCPIP induces angiogenesis by sequential induction of ROS, ER stress and autophagy. ► Knockdown of the postulated process results in blocking of the subsequent step/s. ► Biological events involved in inflammatory angiogenesis mediated by MCPIP are shown.