Inhibition of Aβ25-35-induced cell apoptosis by Low-power-laser-irradiation (LPLI) through promoting Akt-dependent YAP cytoplasmic translocation

► LPLI promotes YAP cytoplasmic translocation in an Akt-dependent manner. ► LPLI protects cell from Aβ25-35-induced apoptosis through Akt activation. ► Activated Akt by LPLI promotes YAP phosphorylation on S127. ► Phosphorylated YAP separates from p73 and inhibits Bax expression. ► LPLI inhibits Aβ25-35-induced apoptosis through Akt/YAP/p73 pathway.