کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10971329 | 1106299 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Serum ferritin and paraoxonase-1 in canine leishmaniosis
ترجمه فارسی عنوان
سرم فریتین و پاراکسوناز-1 در لیشمانیا سگ
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کلمات کلیدی
فریتین، پاراکسوناز-1، لیشمانیوز، سگ،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
Ferritin and paraoxonase-1 (PON-1) were measured in dogs experimentally infected by Leishmania infantum (during experimental infection and following treatment) and also in naturally-infected dogs which presented different degrees of proteinuria. Experimentally-infected dogs were monitored for 7 months post-infection, then treated for 3 months with allopurinol, and their response to therapy was followed for 11 additional months. Naturally-infected dogs were staged based on the urine protein/creatinine (UPC) ratio into three groups as follows: group 1 (non-proteinuric; UPC ratio: <0.2), group 2 (borderline proteinuric; UPC ratio: 0.2-0.5) and group 3 (proteinuric; UPC ratio >0.5). An increase in serum ferritin values and a decrease in PON-1 activity were observed 2 months after infection. Both analytes returned to preinfection values following treatment. Significantly higher concentrations of ferritin were observed in dogs classified as either borderline or proteinuric when compared with non-proteinuric dogs whereas serum PON-1 activity was decreased only in proteinuric dogs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Immunology, Microbiology and Infectious Diseases - Volume 37, Issue 1, January 2014, Pages 23-29
Journal: Comparative Immunology, Microbiology and Infectious Diseases - Volume 37, Issue 1, January 2014, Pages 23-29
نویسندگان
S. Martinez-Subiela, J.J. Cerón, D. Strauss-Ayali, J.D. Garcia-Martinez, F. Tecles, A. Tvarijonaviciute, M. Caldin, G. Baneth,