کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1981590 1539419 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
4-Oxo-(E)-2-hexenal produced by Heteroptera induces permanent locomotive impairment in crickets that correlates with free thiol depletion
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
4-Oxo-(E)-2-hexenal produced by Heteroptera induces permanent locomotive impairment in crickets that correlates with free thiol depletion
چکیده انگلیسی


• Heteropterans produce 4-keto-2-aldehydes that function as anti-predatory defenses.
• 4-Oxo-(E)-2-hexenal (OHE) induces permanent locomotive impairments in crickets.
• Covalent binding of OHE to biologically active thiols is a potential cause affecting insect locomotion.

Heteropterans produce 2-alkenals and 4-keto-2-alkenals that function as defense substances or pheromones. However, in spite of advances in heteropteran chemistry, it is still unclear how these compounds affect insect physiology. We found that exposure to 4-oxo-(E)-2-hexenal (OHE) induced permanent paralysis and death in crickets, an experimental model. The depletion of free thiols in leg tissues of OHE-treated crickets and the in vitro adduct formation of OHE with a thiol compound suggest that covalent binding of OHE to biologically active thiols is a potential cause affecting crickets’ locomotion.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Open Bio - Volume 5, 2015, Pages 319–324
نویسندگان
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