کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2030278 1071061 2008 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Coarse-Grained MD Simulations of Membrane Protein-Bilayer Self-Assembly
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Coarse-Grained MD Simulations of Membrane Protein-Bilayer Self-Assembly
چکیده انگلیسی

SummaryComplete determination of a membrane protein structure requires knowledge of the protein position within the lipid bilayer. As the number of determined structures of membrane proteins increases so does the need for computational methods which predict their position in the lipid bilayer. Here we present a coarse-grained molecular dynamics approach to lipid bilayer self-assembly around membrane proteins. We demonstrate that this method can be used to predict accurately the protein position in the bilayer for membrane proteins with a range of different sizes and architectures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 16, Issue 4, 8 April 2008, Pages 621–630
نویسندگان
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