کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2063949 1544115 2016 10 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
An aquarium hobbyist poisoning: Identification of new palytoxins in Palythoa cf. toxica and complete detoxification of the aquarium water by activated carbon
ترجمه فارسی عنوان
مسمومیت آکواریومی تفننی: شناسایی palytoxins جدید در Palythoa cf. toxica و سم زدایی کامل از آب آکواریوم توسط کربن فعال
کلمات کلیدی
پالیتوکسین؛ Hydroxypalytoxin؛ Deoxypalytoxin؛ LC-HRMS؛ ELISA
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
چکیده انگلیسی


• Inhalatory poisoning of aquarium hobbyist during cleaning of a home aquarium.
• New palytoxins identified in Palythoa cf. toxica causing human poisoning.
• Activated carbon adsorbs 99.7% of palytoxins from aquarium seawater.

Palytoxin (PLTX) is a lethal natural toxin often found in Palythoa zoantharians that, together with its congeners, may induce adverse effects in humans after inhalation of toxic aerosols both in open-air and domestic environments, namely in the vicinity of public and private aquaria. In this study, we describe a poisoning of an aquarium hobbyist who was hospitalized after handling a PLTXs-containing zoantharian hexacoral. Furthermore, we provide evidence for water detoxification. The zoantharian was morphologically and genetically identified as Palythoa cf. toxica (Cnidaria: Anthozoa). Palytoxin itself and two new PLTX congeners, a hydroxyPLTX and a deoxyPLTX, were detected and structurally identified by liquid chromatography high resolution multiple stage mass spectrometry (LC-HRMSn, n = 1, 2). Total and individual toxins were quantified by LC-HRMS and sandwich ELISA both in the zoantharian (93.4 and 96.80 μg/g, respectively) and in the transport water (48.3 and 42.56 μg/mL, respectively), with an excellent mean bias of 1.3% between the techniques. Activated carbon adsorbed 99.7% of PLTXs contained in the seawater and this represents a good strategy for preventing aquarium hobbyist poisonings.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicon - Volume 121, October 2016, Pages 41–50
نویسندگان
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