کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2402261 | 1102735 | 2014 | 6 صفحه PDF | دانلود رایگان |
• We reviewed adverse events of live attenuated Japanese encephalitis vaccine.
• The adverse event rate was 61.24 per million doses.
• Most adverse events are relatively mild, with relatively rare neurologic events.
We reviewed the adverse events following immunization of live attenuated Japanese encephalitis vaccine in Guangdong Province, China. During the period of 2005–2012, 23 million doses of live attenuated Japanese encephalitis vaccine were used and 1426 adverse events were reported (61.24 per million doses); of which, 570 (40%) were classified as allergic reactions (24.48 per million doses), 31 (2%) were neurologic events (1.33 per million doses), and 36 (2.5%) were diagnosed as serious adverse events (1.55 per million doses). This study suggests that the JEV-L has a reasonable safety profile, most adverse events are relatively mild, with relatively rare neurologic events being observed.
Journal: Vaccine - Volume 32, Issue 15, 26 March 2014, Pages 1768–1773