کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2461409 | 1555020 | 2015 | 9 صفحه PDF | دانلود رایگان |
This study reports presence of IgZ transcripts, its ontogeny, tissue distribution and expression following various stimulations/infections in rohu. The derived rohu IgZ sequence clustered together with IgZ of Ctenopharyngodon idella and Cyprinus carpio in phylogenetic analysis. IgZ expression was detected at early developmental stages with higher expression at 1 day post-fertilization, and higher in anterior kidney and lower in skin tissues of juveniles. An inductive expression of IgZ was observed during both Edwardsiella tarda and Dactylogyrus catlaius infections in skin and/or gill tissues. In ConA treated HKLs, the response was prominent at 72 h post-stimulation where as in ConA-PMA treatment, it was higher during early time points. Increased expression of IgZ was found between 24 and 96 hps with formalin-killed Aeromonas hydrophila where as in poly I:C treated HKLs, the level increased at 96 hps. It seems to be the first report describing the functional existence of IgZ in rohu carp.
Journal: Veterinary Immunology and Immunopathology - Volume 166, Issues 3–4, 15 August 2015, Pages 70–78