کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2508208 1117599 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quality of life of patients with Parkinson's disease and neurodegenerative dementia: A nationally representative study
ترجمه فارسی عنوان
کيفيت زندگی بيماران مبتلا به بيماری پارکينسون و دمانس عصبی ـ عصبی: يک مطالعه توصيفی در سطح ملی
کلمات کلیدی
بیماری پارکینسون؛ زوال عقل؛ کیفیت زندگی؛ بیماری تخریب عصبی ADL، فعالیت های زندگی روزمره؛ AHRQ، آژانس تحقیقات و کیفیت بهداشت و درمان؛ CI، فاصله اعتماد؛ HRQoL، کیفیت زندگی مرتبط با سلامت؛ IADL،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
چکیده انگلیسی

BackgroundThe disability inherent to Parkinson's disease and dementia would suggest poor health-related quality of life for patients with these neurodegenerative conditions; however, the extent of disability from a nationally representative data has not been previously available.ObjectivesThis study examined factors associated with the health-related quality of life in patients with Parkinson's disease and dementia using nationally representative samples.MethodsThe study used data from 2002 to 2011 Medical Expenditure Panel Survey (MEPS), a nationally representative survey of households in the United States. The quality of life of patients was captured based on Physical Component Summary (PCS), Mental Component Summary (MCS), Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL). Multivariate regression models were used to compare PCS, MCS, ADL and IADL across the two neurodegenerative conditions after controlling for various sociodemographic and clinical characteristics.ResultsThe weighted study population included 0.80 million (95% Confidence Interval, CI: 0.75–0.85) patients; those with Parkinson's disease accounted for 40.23% and remaining 59.77% were diagnosed with dementia. Mean age of the study population was 74.32 years (Standard Deviation, SD = 11.36). Most of the Parkinson's patients were male (57.70%), whereas most of the dementia patients were females (58.10%). The unadjusted mean PCS was 33.66 and 35.31 in Parkinson's and dementia patients, respectively (P < 0.01). Patients with Parkinson's disease were less likely to seek help for IADL than neurodegenerative dementia (Odds Ratio, OR = 0.68, P = 0.02). Various other individual, biological and environmental factors were also associated with quality of life in patients with Parkinson's disease and neurodegenerative dementia.ConclusionsThis study found that patients with Parkinson's disease had lower PCS and were less likely to seek help for IADL when compared to the patients with neurodegenerative dementia. Knowledge of these factors can be helpful in improving quality of life of patients with neurodegenerative diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Social and Administrative Pharmacy - Volume 12, Issue 4, July–August 2016, Pages 604–613
نویسندگان
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