کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2590353 | 1131736 | 2012 | 9 صفحه PDF | دانلود رایگان |
We investigated whether early life chronic exposure to woodsmoke, using personal passive 48-h carbon monoxide (CO) as an indicator, is associated with children's neurodevelopmental and behavioral performance. CO measures were collected every 3 months from 2002 to 2005 among mother–child dyads during the Randomized Exposure Study of Pollution Indoors and Respiratory Effects (RESPIRE) stove intervention trial in San Marcos, Guatemala. From March to June, 2010, study children of age 6–7 years, performed a follow-up non-verbal, culturally adapted neurodevelopmental assessment. We found inverse associations between CO exposure of pregnant mothers during their 3rd trimesters (m = 3.8 ppm ± 3.0 ppm; range: 0.6–12.5 ppm) and child neuropsychological performance. Scores on 4 out of 11 neuropsychological tests were significantly associated with mothers’ 3rd trimester CO exposures, including visuo-spatial integration (p < 0.05), short-term memory recall (p < 0.05), long-term memory recall (p < 0.05), and fine motor perfor
Journal: NeuroToxicology - Volume 33, Issue 2, March 2012, Pages 246–254