کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2593331 1562159 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pregnancy outcomes following the use of thiocolchicoside
ترجمه فارسی عنوان
نتایج بارداری به دنبال استفاده از thiocolchicoside
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی


• We describe the outcome of 18 pregnancies exposed to thiocolchicoside.
• Of 18 pregnancies, 16 resulted in live births.
• No congenital abnormalities were found in newborns.
• The growth and neurological development were uneventful for the babies at age 2.

Thiocolchicoside is a commonly used muscle relaxant in orthopedic, rheumatologic or musculoskeletal disorders to treat painful muscle spasms. It is contraindicated in pregnancy and lactation. There is no previously published experience with thiocolchicoside exposure during pregnancy. In this observational study, we collected and evaluated 18 pregnancy outcomes of the women referred to our prenatal consultation service for thiocolchicoside exposure between 2007–2012, and offspring were followed up until 2 years of age. There were 16 live births, 1 spontaneous abortion and 1 elective termination of pregnancy. No major birth defect was observed. The mothers and their babies were free of perinatal complications. No growth or developmental abnormalities were found during follow-up period. Our findings add information on inadvertent use of thiocolchicoside in pregnancy. Further large prospective cohort studies are required to investigate this issue.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Toxicology - Volume 60, April 2016, Pages 129–132
نویسندگان
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