کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2628394 1563191 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of Hop (Humulus lupulus L.) on early menopausal symptoms and hot flashes: A randomized placebo-controlled trial
ترجمه فارسی عنوان
اثر هاپ (رازک L.) بر علائم یائسگی زودرس و گرگرفتگی: یک مطالعه کنترل شده با پلاسبو تصادفی
کلمات کلیدی
علایم اولیه یائسگی؛ هاپ (رازک L.)؛ یائسگی؛ کارآزمایی بالینی تصادفی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
چکیده انگلیسی


• This study is the first one which used Hop in tablet form.
• We tried to provide a minimum tolerable dose, appropriate drug form, and convenient use for consumer.
• Results of the present study showed that consumption of Hop tablet dramatically reduced the mean score of the early symptoms of menopause.

ObjectiveThis study aimed to evaluate the efficacy of Hop on early menopausal symptoms and hot flashes.MethodsIn this randomized controlled trial, 120 women were randomly allocated into two groups, receiving the Hop or placebo tablets for 12 weeks. Early menopausal symptoms were assessed using Greene scale and hot flashes were recorded in a diary before, and 4, 8 and 12 weeks after intervention.ResultsThe mean Greene score was significantly lower in the Hop group than the placebo group at the end of weeks 4 (adjusted difference: -10.0, 95% confidence interval: -11.1–−8.9), 8 (−18.6, -20.1–−17.1) and 12 (−23.4, -25.1–−21.6). The number of hot flashes was significantly lower in the Hop group than the control group during the weeks 4 (−8.4, -9.8–−7.1), 8 (−17.1, -14.9–−19.3) and 12 (−23.8, -21.1–−26.4).ConclusionsHop effectively reduced the early menopausal symptoms.Clinical trial registrationThis study was approved (code 91209) by the Ethic Committee of Tabriz university of Medical Sciences and registered at the Iranian registry of clinical trials, with IRCT 2013010110324N7 on April 2013.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Complementary Therapies in Clinical Practice - Volume 23, May 2016, Pages 130–135
نویسندگان
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