Andropause in the Aging Male

Andropause is an age-related decline of testosterone in men that is gaining recognition as the world population becomes more aged. The diagnosis is based on clinical signs and symptoms supported with laboratory confirmation of low serum testosterone levels. The benefit of testosterone replacement therapy (TRT) for andropause has been well documented, but it requires careful monitoring. As the health care community recognizes the prevalence and symptoms of andropause, treatment can be implemented to improve the quality of life for the aging male. This literature review examines current knowledge about the pathophysiology, clinical manifestations, diagnosis and treatment, and clinical recommendations pertaining to andropause.