Optic and Otic Side Effects of Molecular Targeted Therapies

ObjectivesTo discuss the optic and otic toxicities associated with molecular targeted therapies including description, presentation, grading, and management of these toxicities.Data SourcesPubMed, CINAHL, the Cochrane Library and nursing text books.ConclusionAlthough targeted therapies often do not have the same systemic toxicities as chemotherapy, they have their own unique side effects. Optic and otic toxicities are seen with a variety of targeted therapies and, although these are not life-threatening toxicities, they do have the potential to severely impair a patient's quality of life.Implications for Nursing PracticeBaseline optic and otic assessments along with periodic assessments throughout treatment can lead to early recognition of problems with the eyes or ears. Recognition and treatment of these problems will help maintain the patient's quality of life.