کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2687907 1143054 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immobilization of hesperidin on stainless steel surfaces and its blood compatibility
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Immobilization of hesperidin on stainless steel surfaces and its blood compatibility
چکیده انگلیسی

The coating of hesperidin, a traditional Chinese medicine ingredient, was immobilized to the surface of stainless steel (SS) which was often used in the cardiovascular implant materials and evaluated for its blood compatibility in vitro. The immobilized coating showed prolonged activated partial thromboplastin time (APTT), prothrombin time (PT) and thrombin time (TT) values compared with stainless steel control. The platelet adhesion and activation test on the hesperidin coating also showed significantly less data compared with the control. The test on conformational change of fibrinogen (fgn) demonstrated the hesperidin coating could reduce this parameter compared with the bare SS. It can be summarized that the hesperidin coating can effectively improve the blood compatibility of the SS surface. We envisage that this coating will provide a potential and effective selection for blood contact devices.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Preventive Nutrition - Volume 3, Issue 4, October–December 2013, Pages 339–343
نویسندگان
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