کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2760283 | 1150170 | 2013 | 13 صفحه PDF | دانلود رایگان |
ObjectiveThe aim of this study was to compare cognition following coronary artery bypass grafting (CABG) surgery with or without cardiopulmonary bypass (CPB) (on- or off-pump).DesignSystematic review and meta-analysis of randomized control trials comparing cognitive outcome in patients undergoing CABG surgery on- or off-pump as assessed by continuous measures from a battery of 7 psychometric tests.SettingMulti-institutional centers performing CABG surgery.ParticipantsPatients with coronary artery disease requiring CABG surgery.InterventionsCABG surgery with or without CPB.Measurements and main resultsA structured literature search identified 13 randomized control trials that included a total of 2,405 patients. Results from 7 psychometric tests were grouped into early (≤3 months) and late (6-12 months) postoperative periods. No significant differences were found between on- and off-pump groups in any of the 7 psychometric tests in either the early (p range 0.21-0.78) or late (p range 0.09-0.93) postoperative period.ConclusionThe results suggested that CPB may not be associated with cognitive decline that is associated with CABG surgery.
Journal: Journal of Cardiothoracic and Vascular Anesthesia - Volume 27, Issue 2, April 2013, Pages 253–265