کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2780622 1153303 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The population-based prevalence of osteoporotic vertebral fracture and densitometric osteoporosis in postmenopausal women over 50 in Valencia, Spain (the FRAVO Study)
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
The population-based prevalence of osteoporotic vertebral fracture and densitometric osteoporosis in postmenopausal women over 50 in Valencia, Spain (the FRAVO Study)
چکیده انگلیسی

PurposeTo estimate the prevalence of vertebral fracture and densitometric osteoporosis in postmenopausal women over the age of 50 in Valencia, Spain.MethodsThis cross-sectional study was conducted in 2006–2007. An age-stratified population-based random sample of 824 postmenopausal women over the age of 50 answered a questionnaire and received a densitometric examination of the lumbar spine and hip with dual-energy X-ray absorptiometry and a lateral X-ray of the thoracic spine and lumbar regions. Osteoporosis was defined as a T-score less than or equal to − 2.5 compared to a population of young women, and the presence of vertebral fractures was classified according to Genant's semiquantitative method.ResultsThe average age of the women was 64 years (range 50–87 years). The prevalence for all vertebral fractures was 21.4% (95% CI: 17.7%–25.1%) and 9.7% (95% CI: 6.7%–12.7%) for moderate–severe fractures. In women over the age of 75, the respective values were 46.3% (95% CI: 34.2%–58.3%) and 23.9% (95% CI:13.6%–34.2%). Only 1.5% of the women with vertebral fractures were aware of their condition. The prevalence of osteoporosis was estimated as 27.0% (95% CI:23.1%–30.8%) for the lumbar spine, 15.1% (95% CI:11.7%–18.5%) in the femoral neck, and 31.8% (95% CI:27.8%–35.7%) at either sites.ConclusionsThe study confirms that osteoporosis (1 in 3 women over the age of 50) and vertebral fracture (1 in 5 for all fractures and 1 in 10 for moderate–severe fractures) constitute a major public health and healthcare challenge; measuring their real impact will depend in part on the criteria used to define a fracture.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 47, Issue 3, September 2010, Pages 610–616
نویسندگان
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