کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2796803 1155621 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impact of gestational diabetes mellitus screening strategies on perinatal outcomes: A simulation study
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Impact of gestational diabetes mellitus screening strategies on perinatal outcomes: A simulation study
چکیده انگلیسی

AimsTo evaluate the impact on perinatal outcomes of universal gestational diabetes (GDM) screening based on 1999 WHO and IADPSG diagnostic criteria; to assess the quality of the evidence (GRADE) to support GDM screening.MethodsSimulation of a hypothetical cohort of community-based pregnant women with 10% GDM prevalence (1999 WHO). Most parameters were obtained from recent systematic reviews.ResultsCompared to no screening, screening based on 1999 WHO criteria (followed by treatment) reduced the incidence of large for gestational age (LGA) neonates by 0.53% (95% CI 0.37–0.74%; NNS = 189) and of preeclampsia by 0.27% (0.10–0.45%; NNS = 376). Screening based on IADPSG criteria reduced incidences by 0.85% (0.54–1.29%; NNS = 117) and by 0.39% (0.15–0.65%; NNS = 257), respectively. Compared to screening based on 1999 WHO criteria, screening with IADPSG criteria reduced the incidence of LGA by 0.32% (0.09–0.63%; NNS = 309) and of preeclampsia by 0.12% (0.01–0.25; NNS = 808). The quality of evidence for both screening approaches is very low.ConclusionsUniversal screening for GDM has only a modest impact on pregnancy outcomes. The impact of screening based on IADPSG (vs. WHO, 1999) criteria is slightly larger. However, costs and resources should also be considered in local selection of a screening approach.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 99, Issue 3, March 2013, Pages 358–365
نویسندگان
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