کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2797901 1155670 2009 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Endothelial dysfunction and cardiovascular risk factors
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Endothelial dysfunction and cardiovascular risk factors
چکیده انگلیسی

The endothelium plays an integral role in the regulation of vascular tone, platelet activity, leukocyte adhesion, and thrombosis and is intimately involved in the development of atherosclerosis. Endothelial dysfunction has been observed in patients with established coronary artery disease or coronary risk factors, both in the coronary and peripheral vasculature. Therapeutic interventions with lipid-lowering drugs, ACE inhibitors, physical activity, and antioxidant agents have been shown to improve endothelial function in coronary and peripheral vessels. This systemic manifestation and improvement of endothelial function suggests that a common mechanism may contribute to endothelial dysfunction in the coronary and peripheral circulation.Target audience: Internist, Cardiologists, Family physicians.Learning objectives: After completion of this article, the reader should be able to define the participation of cardiovascular risk factors in the various complications associated with endothelial dysfunction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 84, Issue 1, April 2009, Pages 1–10
نویسندگان
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