کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2820713 1160882 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
REMiner: A tool for unbiased mining and analysis of repetitive elements and their arrangement structures of large chromosomes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
REMiner: A tool for unbiased mining and analysis of repetitive elements and their arrangement structures of large chromosomes
چکیده انگلیسی

Repetitive elements (REs) constitute a substantial portion of the genomes of human and other species; however, the RE profiles (type, density, and arrangement) within the individual genomes have not been fully characterized. In this study, we developed an RE analysis tool, called REMiner, for a chromosome-wide investigation into the occurrence of individual REs and arrangement of clusters of REs, and REMiner's functional features were examined using the human chromosome Y. The algorithm implemented by REMiner focused on unbiased mining of REs in large chromosomes and data interface within a viewer. The data from the chromosome demonstrated that REMiner is an efficient tool in regard to its capacity for a large query size and the availability of a high-resolution viewer, featuring instant retrieval of alignment data and control of magnification and identity ratio. The chromosome-wide survey identified a diverse population of ordered RE arrangements, which may participate in the genome biology.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Genomics - Volume 98, Issue 5, November 2011, Pages 381–389
نویسندگان
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