کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2846735 1571302 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Changes in breathing pattern upon 100% oxygen in children at early school age
ترجمه فارسی عنوان
تغییرات در الگوی تنفس در اکسیژن 100٪ در کودکان در سن مدرسه
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
چکیده انگلیسی


• We systematically compared breathing pattern with and without exposure to oxygen.
• We studied 40 children (healthy and former preterm) at early school age.
• Pure oxygen does not systematically influence breathing pattern in that age group.
• Oxygen can be used as tracer gas for multiple breath washout in that age group.

Nitrogen multiple-breath washout (N2MBW) is an increasingly used tidal breathing test in young children to assess ventilation inhomogeneity. However, the test requires 100% oxygen to perform. We aimed to examine the potential influence of pure oxygen on breathing pattern in school-aged children.We performed tidal breathing measurements under room air followed by N2MBW in 16 former preterm children and 24 healthy controls. We compared tidal volume (VT), coefficient of variation of VT (CVVT), respiratory rate (RR), and minute ventilation (VE) between tidal breathing and N2MBW, and between the start and end of tidal breathing. Mean (range) age was 6.8 (5.9, 9.0) years. VT, RR and VE showed no significant change upon oxygen-exposure, while CVVT significantly decreased by 5% (95% CI: 1.2, 9.0; p = 0.012). However CVVT was also the only parameter which significantly decreased during tidal breathing. Overall, pure oxygen has no systematic effect on breathing pattern in young school-aged children. N2MBW can reliably be used as tracer gas in this age group.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 228, July 2016, Pages 9–15
نویسندگان
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