کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2857426 | 1572269 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Relation Between Aortic Knob Calcium Observed by Simple Chest X-Ray or Fluoroscopy and Plaque Components in Patients With Diabetes Mellitus
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
We used virtual histology and intravascular ultrasound (VH-IVUS) to evaluate the relation between aortic knob calcium (AKC) and plaque components in diabetic patients. The presence of AKC was assessed by posteroanterior view of chest x-ray or fluoroscopy at the time of coronary angiography. A total of 137 de novo coronary culprit lesions in 137 consecutive diabetic patients were studied and coronary plaque components were analyzed using VH-IVUS according to the presence (n = 45) or absence (n = 92) of AKC. Patients with AKC were significantly older (68 ± 8 vs 62 ± 9 years, p <0.001) and had significantly higher high-sensitivity C-reactive protein levels (1.97 ± 1.33 vs 0.48 ± 1.35 mg/dl, p = 0.005) compared to patients without AKC. Absolute and percent necrotic core (NC) volumes (30 ± 26 vs 20 ± 19 mm3, p = 0.003; 23.4 ± 10.3% vs 17.4 ± 8.9%, p = 0.005, respectively) and absolute and percent dense calcium (DC) volumes (17 ± 12 vs 11 ± 12 mm3, p = 0.010; 13.3 ± 7.3% vs 9.6 ± 7.9%, p = 0.011, respectively) were significantly greater in lesions with AKC compared to those without AKC. Multivariable analysis showed that age (odds ratio [OR] 1.233, 95% confidence interval [CI] 1.121 to 1.355, p <0.001), high-sensitivity C-reactive protein (OR 1.871, 95% CI 1.090 to 2.943, p = 0.007), absolute DC volume (OR 1.020, 95% CI 1.050 to 1.178, p = 0.003), and absolute NC volume (OR 1.026, 95% CI 1.057 to 1.199, p <0.001) were independent predictors of AKC. In conclusion, diabetic patients with AKC were older, had greater NC- and DC-containing plaques, and higher inflammatory status compared to diabetic patients without AKC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Cardiology - Volume 106, Issue 1, 1 July 2010, Pages 38-43
Journal: The American Journal of Cardiology - Volume 106, Issue 1, 1 July 2010, Pages 38-43
نویسندگان
Young Joon MD, Myung Ho MD, Yun Ha RN, Eun Hye RN, Jum Suk MD, Min Goo MD, Keun Ho MD, Doo Sun MD, Nam Sik MD, Hyun Ju MD, Kye Hun MD, Hyung Wook MD, Ju Han MD, Youngkeun MD, Jeong Gwan MD, Jong Chun MD, Jung Chaee MD,