Diverse Associations of Microalbuminuria With C-Reactive Protein, Interleukin-18 and Soluble CD 40 Ligand in Male Essential Hypertensive Subjects

In essential hypertensive subjects, MA is accompanied by elevated hs-CRP levels, but not by augmented IL-18 and sCD40L concentrations, suggesting activation of different inflammatory pathways in the progression of renal and cardiovascular atherosclerotic disease. The pathophysiologic mechanisms of these associations remain to be further elucidated in future studies.