کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2905256 | 1173424 | 2007 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diagnosis and Treatment of Tuberculous Pleural Effusion in 2006
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کلمات کلیدی
EPTBAFBTh1CXCR3adenosine deaminase - آدنوزین دآمینازinterferon - اینترفرونIFN - اینترفرون هاinterferon-γ - اینترفرون-γinterleukin - اینترلوکینAcid-fast bacilli - باسیل اسید سریعTuberculosis - بیماری سلDiagnosis - تشخیصTreatment - درمانextrapulmonary tuberculosis - سل ریوی بیضهT-helper type 1 - نوع T-helper 1polymerase chain reaction - واکنش زنجیره ای پلیمرازPCR - واکنش زنجیرهٔ پلیمرازADA - وجود داردPathogenesis - پاتونزCorticosteroids - کورتیکواستروئیدها
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Tuberculous (TB) pleural effusion occurs in approximately 5% of patients withMycobacterium tuberculosisinfection. The HIV pandemic has been associated with a doubling of the incidence of extrapulmonary TB, which has resulted in increased recognition of TB pleural effusions even in developed nations. Recent studies have provided insights into the immunopathogenesis of pleural TB, including memory T-cell homing and chemokine activation. The definitive diagnosis of TB pleural effusions depends on the demonstration of acid-fast bacilli in the sputum, pleural fluid, or pleural biopsy specimens. The diagnosis can be established in a majority of patients from the clinical features, pleural fluid examination, including cytology, biochemistry, and bacteriology, and pleural biopsy. Measurement of adenosine deaminase and interferon-γ in the pleural fluid and polymerase chain reaction forM tuberculosishas gained wide acceptance in the diagnosis of TB pleural effusions. Although promising, these tests require further evaluation before their routine use can be recommended. The treatment of TB pleural effusions in patients with HIV/AIDS is essentially similar to that in HIV-negative patients. At present, evidence regarding the use of corticosteroids in the treatment of TB pleural effusion is not clear-cut.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chest - Volume 131, Issue 3, March 2007, Pages 880-889
Journal: Chest - Volume 131, Issue 3, March 2007, Pages 880-889
نویسندگان
Gopi MBBS, Madhavan MD, Sharma MD, PhD, Sahn MD, FCCP,