کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2950816 1577300 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Arrhythmias in a Contemporary Fontan Cohort : Prevalence and Clinical Associations in a Multicenter Cross-Sectional Study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Arrhythmias in a Contemporary Fontan Cohort : Prevalence and Clinical Associations in a Multicenter Cross-Sectional Study
چکیده انگلیسی

ObjectivesOur aim was to examine the prevalence of arrhythmias and identify independent associations of time to arrhythmia development.BackgroundSince introduction of the Fontan operation in 1971, long-term results have steadily improved with newer modifications. However, atrial arrhythmias are frequent and contribute to ongoing morbidity and mortality. Data are lacking regarding the prevalence of arrhythmias and risk factors for their development in the current era.MethodsThe Pediatric Heart Network Fontan Cross-Sectional study evaluated data from 7 centers, with 520 patients age 6 to 18 years (mean 8.6 ± 3.4 years after the Fontan operation), including echocardiograms, electrocardiograms, exercise testing, parent-reported Child Health Questionnaire (CHQ) results, and medical history.ResultsSupraventricular tachycardias were present in 9.4% of patients. Intra-atrial re-entrant tachycardia (IART) was present in 7.3% (32 of 520). The hazard of IART decreased until 4 to 6 years post-Fontan, and then increased with age thereafter. Cardiac anatomy and resting heart rate (including marked bradycardia) were not associated with IART. We identified 3 independent associations of time to occurrence of IART: lower CHQ physical summary score (p < 0.001); predominant rhythm (p = 0.002; highest risk with paced rhythm), and type of Fontan operation (p = 0.037; highest risk with atriopulmonary connection). Time to IART did not differ between patients with lateral tunnel and extracardiac conduit types of Fontan repair. Ventricular tachycardia was noted in 3.5% of patients.ConclusionsOverall prevalence of IART was lower in this cohort (7.3%) than previously reported. Lower functional status, an atriopulmonary connection, and paced rhythm were determined to be independently associated with development of IART after Fontan. (Relationship Between Functional Health Status and Ventricular Performance After Fontan–Pediatric Heart Network; NCT00132782)

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American College of Cardiology - Volume 56, Issue 11, 7 September 2010, Pages 890–896
نویسندگان
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