کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3003584 1180810 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Very low-calorie ketogenic diet may allow restoring response to systemic therapy in relapsing plaque psoriasis
ترجمه فارسی عنوان
رژیم کتوژنیک بسیار کم کالری ممکن است باعث بازگرداندن واکنش به سیستمیک در درمان پسوریازیس پلاکت شود
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

SummaryPsoriasis is a chronic disease associated with overweight/obesity and related cardiometabolic complications. The link between these diseases is likely the inflammatory background associated with adipose tissue, particularly the visceral one. Accordingly, previous studies have demonstrated that in the long-term weight loss may improve the response to systemic therapies. We report a case report of a woman in her 40s suffering from relapsing moderate-to-severe plaque psoriasis and obesity-related metabolic syndrome, in whom adequate response to ongoing treatment with biological therapy (adalimumab) was restored after only 4 weeks of very low-calorie, carbohydrate-free (ketogenic), protein-based diet. Accordingly, through rapid and consistent weight loss, very low calorie ketogenic diet may allow restoring a quick response to systemic therapy in a patient suffering from relapsing psoriasis. This intervention should be considered in overweight/obese patients before the rearrangement of systemic therapy. Nonetheless, studies are required to evaluate whether very low calorie ketogenic diets should be preferred to common low-calorie diets to improve the response to systemic therapy at least in patients with moderate-to-severe psoriasis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Obesity Research & Clinical Practice - Volume 10, Issue 3, May–June 2016, Pages 348–352
نویسندگان
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