Clinical uses of H reflexes of upper and lower limb muscles

• H reflexes can be obtained from many upper and lower limb muscles (e.g., tibialis anterior, the thenar muscles and forearm extensors) during a voluntary contraction of the test muscle.
• The contraction raises motoneuron excitability and decreases the Ib limitation on the reflex.
• H reflexes recorded at rest from muscles for which no reflex can normally be demonstrated is evidence of hyperreflexia, raising suspicion of ALS if there is denervation in that muscle.

H reflexes can be recorded from virtually all muscles that have muscle spindles, but reflex reinforcement may be required for the reflex response to be demonstrable. This can allow conduction across proximal nerve segments and most nerve root segments commonly involved by pathology. Stimulus rate is critical in subjects who are at rest. However the reflex attenuation with higher rates is greatly reduced during a background contraction of the test muscle, with only minor changes in latency if any. In addition the contraction ensures that the reflex response occurs in the desired muscle. Reflex latencies should be corrected for height (or limb length) and age. Because the reflex discharge requires a synchronised volley in group Ia afferents, large increases in reflex latency occur rarely with purely sensory lesions. If the H reflex of soleus, quadriceps femoris or flexor carpi radialis is absent at rest but appears during a voluntary contraction at near-normal latency, there is either low central excitability or a predominantly sensory abnormality. With the former H reflexes will be difficult to elicit throughout the body. If H reflexes can be recorded at rest from muscles for which no reflex can normally be demonstrated, there is good evidence for hyperreflexia. In the context of possible ALS, this is an important finding when there is EMG evidence of chronic partial denervation in that muscle.