کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
3099218 1191091 2016 5 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Comparative efficacy of two polyherbal creams with framycetin sulfate on diabetic wound model in rats
ترجمه فارسی عنوان
اثربخشی مقایسه ای از دو کرم چندگیاهی با سولفات framycetin در مدل زخم دیابتی در موش
کلمات کلیدی
زخم دیابتی؛ مدل برداشتن؛ مدل برش؛ التیام زخم
Diabetic wound; Excision model; Incision model; Wound healing
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
چکیده انگلیسی

BackgroundDiabetes mellitus is one of the metabolic disorders that impede normal steps of wound healing process. Worldwide, 15% of the 200 million diabetics suffer from diabetic wounds. Diabetic complications, such as foot ulcer, impose major public health burdens worldwide.ObjectiveThe present study was carried out to evaluate comparative efficacy of polyherbal creams with framycetin sulfate cream on diabetic rats using incision and excision wound models.Materials and methodsAlloxan (120 mg/kg, intraperitoneal) induced diabetic rat models (incision and excision models) were used to evaluate wound healing effect of cream A, B, and framycetin sulfate. Cream A and B were applied for a period of 10 and 20 days for incision and excision wound models, respectively. Incision wound model was used to assess the effect on breaking strength. Wound contraction and epithelialization period were measured using excision wound model. The data were analyzed by one-way ANOVA followed by Bonferroni post-test.ResultsTensile strength of the animals treated with cream B (941.66 ± 15.36) was found to be significantly greater (P < 0.001) as compared to tensile strength of the animals treated with cream A (825 ± 22.36). Wound treated with cream B was found to heal significantly (P < 0.001) faster (day 17) as compared to wounds treated with framycetin sulfate (day 21).ConclusionsCream B was found to be more effective wound healing agent than cream A and framycetin sulfate cream in treating diabetic wounds.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ayurveda and Integrative Medicine - Volume 7, Issue 2, April–June 2016, Pages 83–87
نویسندگان
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