کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3165079 1198820 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impact of submandibular gland excision on salivary gland function in head and neck cancer patients
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Impact of submandibular gland excision on salivary gland function in head and neck cancer patients
چکیده انگلیسی

SummaryHead and neck cancer surgery is often associated with neck dissection and usually includes the submandibular glands. Literature data related to remaining salivary gland function after surgery is scarce and controversial. A reduction in salivary output and increase in complaints of xerostomia have been suggested. However, a compensatory salivary mechanism has also been reported.The aim of this prospective study was to evaluate the effect of neck dissection (with submandibular excision) on salivary gland function measured by salivary flow rate and salivary gland scintigraphy.A total of 80 patients with head and neck tumors were evaluated. The surgery group was composed of 37 patients, who underwent submandibular gland resection, and the non-surgery group of 43 patients evaluated prior to radiation and/or chemotherapy treatment. Whole unstimulated and stimulated saliva collection and salivary gland scintigraphy were performed in all patients.Twenty-one percent of patients in the surgery group reported xerostomia, whereas 7% in the non-surgery group. The mean unstimulated salivary flow was 0.60 and 0.94 m/min for the surgery and non-surgery groups, respectively (p = 0.008). Nevertheless, no statistical difference in the stimulated salivary flow was observed between the groups (p = 0.26). In addition, the mean uptake and excretion rates for parotid and remaining submandibular glands also showed no statistical difference.The data of the present study support the contention that submandibular gland resection causes a decrease in unstimulated salivary volume. However, the residual submandibular glands in the surgery group showed similar function to that of submandibular glands in the non-surgery group. Consequently, the compensatory salivary mechanism seems not to be a possibility.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 46, Issue 5, May 2010, Pages 349–354
نویسندگان
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