Atherosclerosis: Current perspectives

Atherosclerosis is among greatest concerns of contemporary medical science and care, and its dangerous sequel are common knowledge. Atherosclerosis is not just state of excessive activation of innate but involvement also of adaptive immune responses. Adipose tissue cytokines and their diverse shared biological traits with the immune system counterparts orchestrate an immune mediated inflammatory process. Medical progress in transcript-omics and epi-genetics has primarily been driven in recent years by the subclinical chronic inflammation implied in atherosclerosis. Contemporary evidence based medicine has added obligation to individualized address implying molecular approach to diagnosis and management. The context of new knowledge on pathogenesis and rational remediation is pertinent to update clinical approach to atherosclerosis and its complications. The present narrative attempts to incorporate some current perspects for discussion.