کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
331238 1433644 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients
چکیده انگلیسی

Cognitive impairment in elderly diabetic patients has generated considerable interest recently; however, the mechanism of the impairment remains to be elucidated. In the current study, factors associated with cognitive dysfunction in old diabetic patients were explored. A Mini Mental State Examination (MMSE) was performed on 907 of 1173 registered elderly Japanese diabetic subjects. To characterize the clinical features of diabetes, we examined indices of glycemic control, lipid metabolism, blood pressure and complications. Single regression analysis adjusted for age showed that shorter height, higher GDS 15 scores, lower serum albumin, history of cerebrovascular disease, the existence of diabetic nephropathy, no smoking habit, no drinking habit, and no occupation were associated with lower MMSE scores. Multiple regression analysis demonstrated that age (odds ratio (OR) = 1.079; 95% confidence interval (CI) = 1.011–1.150), GDS 15 scores (OR = 1.139; 95% CI = 1.045–1.243), serum albumin (OR = 0.336; 95% CI = 0.174–0.745), and history of cerebrovascular disease (OR = 3.011; 95% CI = 1.578–5.748) were the variables significantly associated with having lower MMSE scores.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Aging - Volume 29, Issue 7, July 2008, Pages 1022–1026
نویسندگان
, , , , , , , ,