Comparison of efficacy between continuous hemodiafiltration with a PMMA membrane hemofilter and a PAN membrane hemofilter in the treatment of a patient with septic acute renal failure

The aim of this study was to investigate whether PMMA–CHDF in the treatment of a patient with septic acute renal failure (septic ARF) is clinically relevant. Thirteen patients were treated with PMMA–CHDF. Thirteen patients were treated with PAN–CHDF. The urinary output significantly increased in PMMA–CHDF group following 24 h of the treatment (p < 0.05), whereas those did not improve in PAN–CHDF group. The 28-day survival was 84.6% in PMMA–CHDF group and 38.5% in PAN–CHDF group, respectively (p < 0.05). We can assume that the cytokine modulation with PMMA–CHDF in the treatment of patients with septic ARF is clinically relevant.