Antibacterial prophylaxis in neutropenic patients

Antibiotic prophylaxis has been used for several decades to prevent infection in chemotherapy-induced neutropenia and its benefits have been debated just as long. Recent analysis suggests that quinolones may actually be life saving in high-risk groups such as acute leukaemia and autologous bone marrow transplant but these benefits are likely to be negated in the long term by the development of quinolone resistance.