کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3485296 | 1596915 | 2015 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Radiofrequency ablation versus partial nephrectomy for treatment of renal masses: AÂ systematic review and meta-analysis
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
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چکیده انگلیسی
Our study was to collect the data available in the literature on radiofrequency ablation (RFA) and partial nephrectomy (PN) and conduct a cumulative analysis on perioperative outcomes, renal function outcomes, and survival to evaluate the overall safety and efficacy of RFA versus PN for small renal cell cancer (SRCC). A literature search was carried out using various electronic databases. Data including age, tumor size, comorbid disease, operation duration, hospital stay, pre- and postoperative estimated glomerular filtration rate (eGFR), major and minor complications, and local tumor recurrence and metastasis were collected for meta-analysis. Sixteen studies were included for this meta-analysis. The age of patients treated with RFA was significantly older than that of patients treated with PN [weighted mean difference (WMD)Â =Â 5.07 years]. There were more patients with cardiovascular disease in RFA group as compared with PN group [odds ratio (OR)Â =Â 4.24] before treatment. RFA was associated with a shorter length of hospital stay compared with PN (WMDÂ =Â â2.02 days). No significant difference was found in major and minor complications between the two groups (major: ORÂ =Â 0.74; minor: ORÂ =Â 0.45). Preoperative eGFR and eGFR decline in RFA patients was significantly lower than that in PN patients (WMDÂ =Â â7.27 and â4.82, respectively), whereas there was no significant difference in postoperative eGFR (WMDÂ =Â â1.18). The local tumor recurrence rate in RFA group was higher than that in PN group (ORÂ =Â 1.81). However, the distant metastasis rate was no statistical difference between the two groups (ORÂ =Â 1.63). RFA is a suitable therapeutic option for older patients and those at high risk for SRCC because of a low risk of operation and better preservation of renal function.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Kaohsiung Journal of Medical Sciences - Volume 31, Issue 12, December 2015, Pages 649-658
Journal: The Kaohsiung Journal of Medical Sciences - Volume 31, Issue 12, December 2015, Pages 649-658
نویسندگان
Xiu-Wu Pan, Xin-Ming Cui, Hai Huang, Yi Huang, Lin Li, Zhi-Jun Wang, Fa-Jun Qu, Yi Gao, Xin-Gang Cui, Dan-Feng Xu,