کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3811510 | 1245774 | 2016 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Méningiomes multiples
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Multiple meningiomas (MMs) or meningiomatosis are defined by the presence of at least 2Â lesions that appear simultaneously or not, at different intracranial locations, without the association of neurofibromatosis. They present 1-9Â % of meningiomas with a female predominance. The occurrence of multiple meningiomas is not clear. There are 2Â main hypotheses for their development, one that supports the independent evolution of these tumors and the other, completely opposite, that suggests the propagation of tumor cells of a unique clone transformation, through cerebrospinal fluid. NF2Â gene mutation is an important intrinsic risk factor in the etiology of multiple meningiomas and some exogenous risk factors have been suspected but only ionizing radiation exposure has been proven. These tumors can grow anywhere in the skull but they are more frequently observed in supratentorial locations. Their histologic types are similar to unique meningiomas of psammomatous, fibroblastic, meningothelial or transitional type and in most cases are benign tumors. The prognosis of these tumors is eventually good and does not differ from the unique tumors except for the cases of radiation-induced multiple meningiomas, in the context of NF2Â or when diagnosed in children where the outcome is less favorable. Each meningioma lesion should be dealt with individually and their multiple character should not justify their resection at all costs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurochirurgie - Volume 62, Issue 3, June 2016, Pages 128-135
Journal: Neurochirurgie - Volume 62, Issue 3, June 2016, Pages 128-135
نویسندگان
L.-M. Terrier, P. François,