Assessment of significant factors affecting acceptability of home administration of misoprostol for medical abortion

BackgroundKnowledge on factors affecting acceptability of medical abortion with mifepristone followed by home administration of misoprostol is scarce. The objective of this study was therefore to assess factors affecting acceptability and experience of home use of misoprostol for medical abortion up to 63 days' gestation.Study DesignProspective observational study with acceptability assessed through questionnaires. Factors affecting acceptability were analyzed using multivariate logistic regression.ResultsA total of 395 women were included. Independent factors for acceptability were having a partner/friend present and having a positive low-sensitivity urine hCG at follow-up, although most of these patients had successful abortions. Age, gestational length and requirement of extra pain medication did not affect acceptability.ConclusionHome administration of misoprostol is highly acceptable. Increasing the number of complete abortions should be a focus of future research. Women should be encouraged to have a partner/friend present during home administration of misoprostol.